Pesticides as a risk factor for metabolic syndrome: Population-based longitudinal study in Korea

Sung Kyung Kim, Sungjin Park, Sei Jin Chang, Soo Ki Kim, Jae Seok Song, Hyoung Ryoul Kim, Sung Soo Oh, Sang Baek Koh

Research output: Contribution to journalArticlepeer-review

10 Citations (Scopus)


Backgrounds: Metabolic syndrome (MetS) is an adverse health effect that can be associated with pesticide exposure. However, there are few epidemiologic studies on the relationship between pesticide use and MetS incidence. Methods: We examined the causal relationship between pesticide use and MetS incidence in a rural population. We used Data from the Korea Farmers Cohort study of 1,162 participants. Poisson regression with a robust error variance was used to calculate relative risks (RRs) and 95% confidence intervals (CIs) to estimate the relationship between pesticide exposure and MetS. Results: The incidence of MetS was 20.7%. Pesticide use increased the RR of MetS incidence. In women, we observed a low-dose effect related to MetS and pesticide exposure. Conclusion: Pesticide exposure was related to the incidence of MetS; the causal relationship differed in men and women.

Original languageEnglish
Pages (from-to)431-441
Number of pages11
JournalMolecular and Cellular Toxicology
Issue number4
Publication statusPublished - 2019 Oct 1

Bibliographical note

Publisher Copyright:
© 2019, The Korean Society of Toxicogenomics and Toxicoproteomics and Springer nature B.V.

All Science Journal Classification (ASJC) codes

  • Pathology and Forensic Medicine
  • Toxicology
  • Pharmacology, Toxicology and Pharmaceutics(all)
  • Public Health, Environmental and Occupational Health
  • Health, Toxicology and Mutagenesis


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