Osteonecrosis of the jaw related to everolimus: A case report

Dong Wook Kim; Young Soo Jung; Hyung Sik Park; Hwi Dong Jung

doi:10.1016/j.bjoms.2013.09.008

Osteonecrosis of the jaw related to everolimus: A case report

Dong Wook Kim, Young Soo Jung, Hyung Sik Park, Hwi Dong Jung

Department of Oral and Maxillofacial Surgery

Research output: Contribution to journal › Article › peer-review

39 Citations (Scopus)

Abstract

Antiresorptive agent-related osteonecrosis of the jaw results in appreciable morbidity in affected patients. Nowadays many physicians prescribe an antiangiogenic agent for the management of malignant metastases. Everolimus is a serine-threonine kinase that acts as an inhibitor of mammalian target of rapamycin, which results in reduced growth of cells, angiogenesis, and survival of cells. We report the first case to our knowledge of osteonecrosis of the jaw that seemed to result from the additive effect of everolimus.

Original language	English
Pages (from-to)	e302-e304
Journal	British Journal of Oral and Maxillofacial Surgery
Volume	51
Issue number	8
DOIs	https://doi.org/10.1016/j.bjoms.2013.09.008
Publication status	Published - 2013 Dec

All Science Journal Classification (ASJC) codes

Surgery
Oral Surgery
Otorhinolaryngology

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10.1016/j.bjoms.2013.09.008

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Osteonecrosis of the jaw related to everolimus: A case report

Abstract

All Science Journal Classification (ASJC) codes

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