Organoids for Advanced Therapeutics and Disease Models

Suran Kim; Ann Na Cho; Sungjin Min; Sooyeon Kim; Seung Woo Cho

doi:10.1002/adtp.201800087

Organoids for Advanced Therapeutics and Disease Models

Suran Kim, Ann Na Cho, Sungjin Min, Sooyeon Kim, Seung Woo Cho

Research output: Contribution to journal › Review article › peer-review

22 Citations (Scopus)

Abstract

Organoid culture is a fast-emerging technology in the biological and biomedical research fields, garnering interest due to its unique features of self-organization from diverse types of stem cells and close resemblance to organs in the human body. This innovative in vitro model system presents the possibility of significant advances in the understanding of human development and disease mechanisms as well as in the discovery of novel diagnostics and therapeutics. Here, the authors review several types of tissue-specific organoids and discuss the most recent studies on the biomedical application of organoids. Finally, the challenges and prospects of organoids as an in vitro model system are laid out.

Original language	English
Article number	1800087
Journal	Advanced Therapeutics
Volume	2
Issue number	1
DOIs	https://doi.org/10.1002/adtp.201800087
Publication status	Published - 2019 Jan

Bibliographical note

Funding Information:
This work was supported by grants (2017M3C7A1047659 and 2018M3A9H1021382) from the National Research Foundation of Korea (NRF) funded by the Ministry of Science and ICT (MSIT), Republic of Korea.

Publisher Copyright:
© 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim

All Science Journal Classification (ASJC) codes

Medicine (miscellaneous)
Pharmacology
Pharmaceutical Science
Genetics(clinical)
Biochemistry, medical
Pharmacology (medical)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1002/adtp.201800087

Cite this

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abstract = "Organoid culture is a fast-emerging technology in the biological and biomedical research fields, garnering interest due to its unique features of self-organization from diverse types of stem cells and close resemblance to organs in the human body. This innovative in vitro model system presents the possibility of significant advances in the understanding of human development and disease mechanisms as well as in the discovery of novel diagnostics and therapeutics. Here, the authors review several types of tissue-specific organoids and discuss the most recent studies on the biomedical application of organoids. Finally, the challenges and prospects of organoids as an in vitro model system are laid out.",

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doi = "10.1002/adtp.201800087",

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AU - Min, Sungjin

AU - Kim, Sooyeon

AU - Cho, Seung Woo

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Organoids for Advanced Therapeutics and Disease Models

Abstract

Bibliographical note

All Science Journal Classification (ASJC) codes

UN SDGs

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