Oral administration of fingerroot (Boesenbergia pandurata) extract reduces ultraviolet b-induced skin aging in hairless mice

Sungkyung Kim; Hyun In Oh; Jae Kwan Hwang

doi:10.1007/s10068-012-0233-8

Oral administration of fingerroot (Boesenbergia pandurata) extract reduces ultraviolet b-induced skin aging in hairless mice

Sungkyung Kim, Hyun In Oh, Jae Kwan Hwang

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

Abstract

Fingerroot [Boesenbergia pandurata (Roxb.) Schltr.], belonging to Zingiberaceae, is an edible tropical medicinal plant that has been traditionally used to treat various diseases. However, the effect of its oral intake on skin has not yet been reported. This study aimed to investigate anti-photoaging effects of the ethanol extract of fingerroot in a hairless mouse model. Compared with the untreated UVB control group, mice that received fingerroot extract (BPE) showed significantly reduced wrinkle formation, skin thickening, and transepidermal water loss in dorsal skin irradiated with UVB. Moreover, BPE significantly prevented UVB-induced matrix metalloproteinase (MMP)-3 and -13 expressions and also MMP-2 and -9 activities. These results strongly suggest that oral administration of BPE confers in vivo anti-photoaging effects in hairless mice. Thus, fingerroot may have potential as an oral photoprotective agent to prevent skin photoaging following UV exposure.

Original language	English
Pages (from-to)	1753-1760
Number of pages	8
Journal	Food Science and Biotechnology
Volume	21
Issue number	6
DOIs	https://doi.org/10.1007/s10068-012-0233-8
Publication status	Published - 2012 Dec

All Science Journal Classification (ASJC) codes

Biotechnology
Food Science
Applied Microbiology and Biotechnology

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10.1007/s10068-012-0233-8

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title = "Oral administration of fingerroot (Boesenbergia pandurata) extract reduces ultraviolet b-induced skin aging in hairless mice",

abstract = "Fingerroot [Boesenbergia pandurata (Roxb.) Schltr.], belonging to Zingiberaceae, is an edible tropical medicinal plant that has been traditionally used to treat various diseases. However, the effect of its oral intake on skin has not yet been reported. This study aimed to investigate anti-photoaging effects of the ethanol extract of fingerroot in a hairless mouse model. Compared with the untreated UVB control group, mice that received fingerroot extract (BPE) showed significantly reduced wrinkle formation, skin thickening, and transepidermal water loss in dorsal skin irradiated with UVB. Moreover, BPE significantly prevented UVB-induced matrix metalloproteinase (MMP)-3 and -13 expressions and also MMP-2 and -9 activities. These results strongly suggest that oral administration of BPE confers in vivo anti-photoaging effects in hairless mice. Thus, fingerroot may have potential as an oral photoprotective agent to prevent skin photoaging following UV exposure.",

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AU - Kim, Sungkyung

AU - Oh, Hyun In

AU - Hwang, Jae Kwan

PY - 2012/12

Y1 - 2012/12

N2 - Fingerroot [Boesenbergia pandurata (Roxb.) Schltr.], belonging to Zingiberaceae, is an edible tropical medicinal plant that has been traditionally used to treat various diseases. However, the effect of its oral intake on skin has not yet been reported. This study aimed to investigate anti-photoaging effects of the ethanol extract of fingerroot in a hairless mouse model. Compared with the untreated UVB control group, mice that received fingerroot extract (BPE) showed significantly reduced wrinkle formation, skin thickening, and transepidermal water loss in dorsal skin irradiated with UVB. Moreover, BPE significantly prevented UVB-induced matrix metalloproteinase (MMP)-3 and -13 expressions and also MMP-2 and -9 activities. These results strongly suggest that oral administration of BPE confers in vivo anti-photoaging effects in hairless mice. Thus, fingerroot may have potential as an oral photoprotective agent to prevent skin photoaging following UV exposure.

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Oral administration of fingerroot (Boesenbergia pandurata) extract reduces ultraviolet b-induced skin aging in hairless mice

Abstract

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