To determine the optimal acquisition time of [18F]Mefway PET, we examined the regional specific-to-nonspecific binding ratios and evaluated the relationship between distribution volume ratios (DVRs) and standardized uptake value ratios (SUVRs) in various time windows. The specific-to-nonspecific binding ratios peaked after 40min and there was a strong correlation between DVR and SUVR in the 60-80min. Therefore, we recommend the use of a single time point between 60 and 80min for [18F]Mefway static PET.
Bibliographical noteFunding Information:
This study was supported by a 2014 faculty research Grant from Yonsei University College of Medicine ( 6-2014-0030 ).
© 2015 Elsevier Ltd.
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