Optimal Rhythm Control Strategy in Patients With Atrial Fibrillation

Daehoon Kim, Pil Sung Yang, Boyoung Joung

Research output: Contribution to journalReview articlepeer-review

10 Citations (Scopus)


For almost 20 years, data regarding the effect of rhythm control therapy for atrial fibrillation (AF) on cardiovascular prognosis in comparison with rate control therapy has not been conclusive. The safety of rhythm control and anticoagulation therapy has generally improved. Recently, it was revealed that a rhythm-control strategy reduced the risk of adverse cardiovascular events than usual rate control in patients with recent AF (diagnosed within 1 year). Within 1 year after the AF diagnosis, early initiation of rhythm control led to more favorable cardiovascular outcomes than rate control. Early rhythm control reduced the risks of stroke and heart failure-related admission than rate control. Moreover, rhythm control was associated with lower dementia risk than rate control. Finally, early rhythm control treatment was also effective in patients with asymptomatic AF but less effective in older adults. Therefore, in patients with AF, rhythm control should be considered at earlier stages, regardless of symptom.

Original languageEnglish
Pages (from-to)496-512
Number of pages17
JournalKorean Circulation Journal
Publication statusPublished - 2022 Jul

Bibliographical note

Publisher Copyright:
© 2022. The Korean Society of Cardiology

All Science Journal Classification (ASJC) codes

  • Internal Medicine
  • Cardiology and Cardiovascular Medicine


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