One-Pot, Three-Component Approach to Diarylmethylphosphonates: A Direct Entry to Polycyclic Aromatic Systems

Sure Siva Prasad; DIleep Kumar Singh; Ikyon Kim

doi:10.1021/acs.joc.9b00668

One-Pot, Three-Component Approach to Diarylmethylphosphonates: A Direct Entry to Polycyclic Aromatic Systems

Sure Siva Prasad, DIleep Kumar Singh, Ikyon Kim

Department of Pharmacy

Research output: Contribution to journal › Article › peer-review

10 Citations (Scopus)

Abstract

A new type of three-component reaction was developed consisting of aldehydes, electron-rich (hetero)arenes, and trialkyl phosphite, which provided facile access to a wide range of diarylmethylphosphonates under mild reaction conditions. Simple one- or two-step synthetic manipulation of the resulting compounds enabled us to reach several polycyclic (hetero)aromatic systems efficiently.

Original language	English
Pages (from-to)	6323-6336
Number of pages	14
Journal	Journal of Organic Chemistry
Volume	84
Issue number	10
DOIs	https://doi.org/10.1021/acs.joc.9b00668
Publication status	Published - 2019 May 17

Bibliographical note

Funding Information:
We thank the National Research Foundation of Korea (NRF-2017R1A2A2A05069364 and NRF-2018R1A6A1A03023718) for generous financial support.

Publisher Copyright:
© 2019 American Chemical Society.

All Science Journal Classification (ASJC) codes

Organic Chemistry

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10.1021/acs.joc.9b00668

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abstract = "A new type of three-component reaction was developed consisting of aldehydes, electron-rich (hetero)arenes, and trialkyl phosphite, which provided facile access to a wide range of diarylmethylphosphonates under mild reaction conditions. Simple one- or two-step synthetic manipulation of the resulting compounds enabled us to reach several polycyclic (hetero)aromatic systems efficiently.",

author = "Prasad, {Sure Siva} and Singh, {DIleep Kumar} and Ikyon Kim",

note = "Funding Information: We thank the National Research Foundation of Korea (NRF-2017R1A2A2A05069364 and NRF-2018R1A6A1A03023718) for generous financial support. Publisher Copyright: {\textcopyright} 2019 American Chemical Society.",

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doi = "10.1021/acs.joc.9b00668",

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AU - Singh, DIleep Kumar

AU - Kim, Ikyon

N1 - Funding Information: We thank the National Research Foundation of Korea (NRF-2017R1A2A2A05069364 and NRF-2018R1A6A1A03023718) for generous financial support. Publisher Copyright: © 2019 American Chemical Society.

PY - 2019/5/17

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N2 - A new type of three-component reaction was developed consisting of aldehydes, electron-rich (hetero)arenes, and trialkyl phosphite, which provided facile access to a wide range of diarylmethylphosphonates under mild reaction conditions. Simple one- or two-step synthetic manipulation of the resulting compounds enabled us to reach several polycyclic (hetero)aromatic systems efficiently.

AB - A new type of three-component reaction was developed consisting of aldehydes, electron-rich (hetero)arenes, and trialkyl phosphite, which provided facile access to a wide range of diarylmethylphosphonates under mild reaction conditions. Simple one- or two-step synthetic manipulation of the resulting compounds enabled us to reach several polycyclic (hetero)aromatic systems efficiently.

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One-Pot, Three-Component Approach to Diarylmethylphosphonates: A Direct Entry to Polycyclic Aromatic Systems

Abstract

Bibliographical note

All Science Journal Classification (ASJC) codes

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