One-pot, three-component approach to diarylacetonitriles

Dileep Kumar Singh, Sure Siva Prasad, Jinhwang Kim, Ikyon Kim

Research output: Contribution to journalArticlepeer-review

13 Citations (Scopus)


Described herein is a novel one-pot, three-component reaction where aldehydes, electron-rich arenes, and TMSCN in the presence of BF 3 -OEt 2 allowed direct access to a number of diarylacetonitriles under mild reaction conditions in good to excellent yields. Implementation of this assembly protocol to a concise synthetic approach to shoreaphenol, a bioactive oligostilbenoid natural product, is also demonstrated.

Original languageEnglish
Pages (from-to)669-673
Number of pages5
JournalOrganic Chemistry Frontiers
Issue number5
Publication statusPublished - 2019 Mar 7

Bibliographical note

Funding Information:
We thank the National Research Foundation of Korea (NRF-2017R1A2A2A05069364 and NRF-2018R1A6A1A03023718) for generous financial support.

Publisher Copyright:
© 2019 the Partner Organisations.

All Science Journal Classification (ASJC) codes

  • Organic Chemistry


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