One-pot access to 2-amino-3-arylbenzofurans: Direct entry to polyheterocyclic chemical space

Sure Siva Prasad; Dirgha Raj Joshi; Jeong Hwa Lee; Ikyon Kim

doi:10.1039/d0ob01715a

One-pot access to 2-amino-3-arylbenzofurans: Direct entry to polyheterocyclic chemical space

Sure Siva Prasad, Dirgha Raj Joshi, Jeong Hwa Lee, Ikyon Kim

Department of Pharmacy

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Abstract

As a means to make new benzofuran-embedded polycyclic structures, we established two efficient one-pot sequential coupling routes to 2-amino-3-arylbenzofurans and 2-amino-3-arylnaphtho[2,1-b]furans. Further ring formation (six- and seven-membered rings) with the resulting amine moiety at the C2 position of benzofurans was realized, leading to further expansion of benzofuran-based chemical space.

Original language	English
Pages (from-to)	8119-8140
Number of pages	22
Journal	Organic and Biomolecular Chemistry
Volume	18
Issue number	40
DOIs	https://doi.org/10.1039/d0ob01715a
Publication status	Published - 2020 Oct 28

Bibliographical note

Funding Information:
We thank the National Research Foundation of Korea (NRF-2018R1A6A1A03023718 and NRF-2020R1A2C2005961) for generous financial support.

Publisher Copyright:
© The Royal Society of Chemistry.

All Science Journal Classification (ASJC) codes

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

Access to Document

10.1039/d0ob01715a

Cite this

@article{9ce1e18e656140eab9102305c4008308,

title = "One-pot access to 2-amino-3-arylbenzofurans: Direct entry to polyheterocyclic chemical space",

abstract = "As a means to make new benzofuran-embedded polycyclic structures, we established two efficient one-pot sequential coupling routes to 2-amino-3-arylbenzofurans and 2-amino-3-arylnaphtho[2,1-b]furans. Further ring formation (six- and seven-membered rings) with the resulting amine moiety at the C2 position of benzofurans was realized, leading to further expansion of benzofuran-based chemical space.",

author = "Prasad, {Sure Siva} and Joshi, {Dirgha Raj} and Lee, {Jeong Hwa} and Ikyon Kim",

note = "Funding Information: We thank the National Research Foundation of Korea (NRF-2018R1A6A1A03023718 and NRF-2020R1A2C2005961) for generous financial support. Publisher Copyright: {\textcopyright} The Royal Society of Chemistry.",

year = "2020",

month = oct,

day = "28",

doi = "10.1039/d0ob01715a",

language = "English",

volume = "18",

pages = "8119--8140",

journal = "Organic and Biomolecular Chemistry",

issn = "1477-0520",

publisher = "Royal Society of Chemistry",

number = "40",

}

TY - JOUR

T1 - One-pot access to 2-amino-3-arylbenzofurans

T2 - Direct entry to polyheterocyclic chemical space

AU - Prasad, Sure Siva

AU - Joshi, Dirgha Raj

AU - Lee, Jeong Hwa

AU - Kim, Ikyon

N1 - Funding Information: We thank the National Research Foundation of Korea (NRF-2018R1A6A1A03023718 and NRF-2020R1A2C2005961) for generous financial support. Publisher Copyright: © The Royal Society of Chemistry.

PY - 2020/10/28

Y1 - 2020/10/28

N2 - As a means to make new benzofuran-embedded polycyclic structures, we established two efficient one-pot sequential coupling routes to 2-amino-3-arylbenzofurans and 2-amino-3-arylnaphtho[2,1-b]furans. Further ring formation (six- and seven-membered rings) with the resulting amine moiety at the C2 position of benzofurans was realized, leading to further expansion of benzofuran-based chemical space.

AB - As a means to make new benzofuran-embedded polycyclic structures, we established two efficient one-pot sequential coupling routes to 2-amino-3-arylbenzofurans and 2-amino-3-arylnaphtho[2,1-b]furans. Further ring formation (six- and seven-membered rings) with the resulting amine moiety at the C2 position of benzofurans was realized, leading to further expansion of benzofuran-based chemical space.

UR - http://www.scopus.com/inward/record.url?scp=85094220610&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85094220610&partnerID=8YFLogxK

U2 - 10.1039/d0ob01715a

DO - 10.1039/d0ob01715a

M3 - Article

C2 - 33016294

AN - SCOPUS:85094220610

SN - 1477-0520

VL - 18

SP - 8119

EP - 8140

JO - Organic and Biomolecular Chemistry

JF - Organic and Biomolecular Chemistry

IS - 40

ER -

One-pot access to 2-amino-3-arylbenzofurans: Direct entry to polyheterocyclic chemical space

Abstract

Bibliographical note

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this