Occlusion of large atrial septal defects with a centering buttoned device: Early clinical experience

Eleftherios B. Sideris, Maurice Leung, Jung Han Yoon, Chuan Rong Chen, Rajeev Lochan, Anne Marie Worms, Christian Rey, Bernhard Meier

Research output: Contribution to journalArticlepeer-review

49 Citations (Scopus)


A feasibility clinical study was conducted for the transcatheter occlusion of large ostium secundum atrial septal defects with the centering buttoned device. The centering buttoned device is a modification of the regular buttoned device in which e centering counter-occluder is sutured at the central 40% portion of the occluder. During centering it la stretched, forming a parachute-shaped structure and pulling the occluder over the center of the defect. During buttoning, the counter-occluder forms a double figure eight, opposing the right atrial side of the atrial capture. Occlusion was performed in 12 patients aged 6 to 56 years. All had been rejected for transcatheter occlusion by the regular buttoned device, because of either their detect size or the lack of adequate septal rim. The defect size varied between 23 and 31 mm, and the device size varied between 45 and 60 mm. Nine had immediate effective occlusions of their defects and three residual shunts. One patient with unbuttoning had hemolysis at 2 weeks and underwent surgery. Early results of the transcatheter occlusion of large atrial septal defects are promising, and larger clinical trials are justified.

Original languageEnglish
Pages (from-to)356-359
Number of pages4
JournalAmerican heart journal
Issue number2
Publication statusPublished - 1996

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine


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