TY - JOUR
T1 - Normal reference values for left atrial strain and its determinants from a large Korean multicenter registry
AU - Sun, Byung Joo
AU - Park, Jae Hyeong
AU - Lee, Minyeong
AU - Choi, Jin Oh
AU - Lee, Ju Hee
AU - Shin, Mi Seung
AU - Kim, Mi Jeong
AU - Jung, Hae Ok
AU - Park, Jeong Rang
AU - Sohn, Il Suk
AU - Kim, Hyungseop
AU - Kim, Hyung Kwan
AU - Cho, Goo Yeong
AU - Park, Jin Sun
AU - Shim, Chi Young
AU - Shin, Sung Hee
AU - Kim, Kye Hun
AU - Kim, Woo Shik
AU - Park, Seung Woo
N1 - Publisher Copyright:
© 2020 Korean Society of Echocardiography.
PY - 2020
Y1 - 2020
N2 - BACKGROUND: Left atrial (LA) strain is a novel parameter of LA function. However, its reference value has not been established, and the determining factors for LA strain remain elusive. We aimed to present LA strain with reservoir, conduit, and contractile components and associated parameters in a large-sized group of healthy individuals. METHODS: The present study was from a prospective multicenter registry in South Korea. Subjects who had no history of cardiovascular disease with adequate images were eligible for inclusion. LA reservoir, conduit, and contractile strains (LASRES, LASCD and LASCT, respectively) were measured. Left ventricular global longitudinal strain (LV GLS) and early and late diastolic strain rates (DSRe and DSRa, respectively) were also evaluated. RESULTS: Among a total of 324 subjects (mean age: 49 ± 16 years, 167 females), the mean LASRES, LASCD, and LASCT values were 35.9% ± 10.6%, 21.9% ± 9.3%, and 13.9% ± 3.6%, respectively. Mean LV GLS was-20.4% ± 2.2%, and mean DSRe and DSRa were 1.6 ± 0.4 s-1 and 0.8 ± 0.3 s-1, respectively. With aging, LASRES and LASCD showed significant decreases. Factors showing independent associations with LASRES were age (B =-0.425, p < 0.001), DSRe (B = 4.706, p = 0.001), and LV GLS (B =-1.081, p < 0.001). Age (B =-0.319, p < 0.001), DSRe (B = 4.140, p = 0.002), DSRa (B =-3.409, p = 0.018), and LV GLS (B =-0.783, p < 0.001) showed associations with LASCD. With LASCT, only DSRa showed a correlation (R = 0.277, p < 0.001). CONCLUSIONS: We presented LA strain in a large-sized group of healthy subjects. Age is a significant determinant of LA function. Associations of LA strain with diastolic strain rates and LV GLS reflect cardiac mechanics.
AB - BACKGROUND: Left atrial (LA) strain is a novel parameter of LA function. However, its reference value has not been established, and the determining factors for LA strain remain elusive. We aimed to present LA strain with reservoir, conduit, and contractile components and associated parameters in a large-sized group of healthy individuals. METHODS: The present study was from a prospective multicenter registry in South Korea. Subjects who had no history of cardiovascular disease with adequate images were eligible for inclusion. LA reservoir, conduit, and contractile strains (LASRES, LASCD and LASCT, respectively) were measured. Left ventricular global longitudinal strain (LV GLS) and early and late diastolic strain rates (DSRe and DSRa, respectively) were also evaluated. RESULTS: Among a total of 324 subjects (mean age: 49 ± 16 years, 167 females), the mean LASRES, LASCD, and LASCT values were 35.9% ± 10.6%, 21.9% ± 9.3%, and 13.9% ± 3.6%, respectively. Mean LV GLS was-20.4% ± 2.2%, and mean DSRe and DSRa were 1.6 ± 0.4 s-1 and 0.8 ± 0.3 s-1, respectively. With aging, LASRES and LASCD showed significant decreases. Factors showing independent associations with LASRES were age (B =-0.425, p < 0.001), DSRe (B = 4.706, p = 0.001), and LV GLS (B =-1.081, p < 0.001). Age (B =-0.319, p < 0.001), DSRe (B = 4.140, p = 0.002), DSRa (B =-3.409, p = 0.018), and LV GLS (B =-0.783, p < 0.001) showed associations with LASCD. With LASCT, only DSRa showed a correlation (R = 0.277, p < 0.001). CONCLUSIONS: We presented LA strain in a large-sized group of healthy subjects. Age is a significant determinant of LA function. Associations of LA strain with diastolic strain rates and LV GLS reflect cardiac mechanics.
KW - LA function
KW - LA strain
KW - Speckle-tracking echocardiography
UR - http://www.scopus.com/inward/record.url?scp=85087090106&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85087090106&partnerID=8YFLogxK
U2 - 10.4250/jcvi.2020.0043
DO - 10.4250/jcvi.2020.0043
M3 - Article
AN - SCOPUS:85087090106
SN - 2586-7210
VL - 28
SP - 186
EP - 198
JO - Journal of Cardiovascular Imaging
JF - Journal of Cardiovascular Imaging
IS - 3
ER -
