TY - JOUR
T1 - Non-aqueous capillary electrophoretic separation and detection of 6H-pyrimido[2,1-a]isoindoles
AU - Pumera, Martin
AU - Horká, Veronika
AU - Nesměrák, Karel
PY - 2002
Y1 - 2002
N2 - A non-aqueous capillary electrophoresis system for separating and detecting antidepressant drugs based on the coupling of capillary electrophoresis separation in acetonitrile and UV detection is described. The system offers a rapid simultaneous measurement in less than 12 min for six priority pyrimidoisoindoles. These antidepressants were detected down to the 2.5 × 10 -6-4.2 × 10 -6 mol/L level, with linearity up to the 1 × 10 -3 mol/L level examined. A highly stable response was observed for repetitive injections (R.S.D. < 2.6%, n = 12). The influence of pH and content of acetonitrile upon the electrophoretic mobilities was also studied.
AB - A non-aqueous capillary electrophoresis system for separating and detecting antidepressant drugs based on the coupling of capillary electrophoresis separation in acetonitrile and UV detection is described. The system offers a rapid simultaneous measurement in less than 12 min for six priority pyrimidoisoindoles. These antidepressants were detected down to the 2.5 × 10 -6-4.2 × 10 -6 mol/L level, with linearity up to the 1 × 10 -3 mol/L level examined. A highly stable response was observed for repetitive injections (R.S.D. < 2.6%, n = 12). The influence of pH and content of acetonitrile upon the electrophoretic mobilities was also studied.
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U2 - 10.1002/1615-9314(20020501)25:7<443::AID-JSSC443>3.0.CO;2-7
DO - 10.1002/1615-9314(20020501)25:7<443::AID-JSSC443>3.0.CO;2-7
M3 - Article
AN - SCOPUS:0036262437
SN - 1615-9306
VL - 25
SP - 443
EP - 446
JO - Journal of Separation Science
JF - Journal of Separation Science
IS - 7
ER -