Necessity of Axillary Scanning After Negative Finding on Both Mammography and Subsequent Breast Ultrasound

Inyoung Youn; Jung Hyun Yoon; Ji Hyun Youk; Hee Jung Moon; Min Jung Kim; Eun Kyung Kim; Jai Kyung You

doi:10.1016/j.ultrasmedbio.2017.08.1888

Necessity of Axillary Scanning After Negative Finding on Both Mammography and Subsequent Breast Ultrasound

Inyoung Youn, Jung Hyun Yoon, Ji Hyun Youk, Hee Jung Moon, Min Jung Kim, Eun Kyung Kim, Jai Kyung You

Department of Radiology

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

The purpose of our study was to assess the cancer detection rate and positive predictive value (PPV) for incidentally detected abnormal axillary lymph nodes with negative mammography and subsequent breast ultrasound (US). We included 7039 screened patients (mean age, 52 y) from January 2012 to March 2015 with negative mammography and subsequent breast US results. In two patients with positive lymph nodes, neither were from breast malignancy. The calculated cancer detection rate, PPV for biopsy and axillary biopsy rate was 0.3 per 1000 axillary US, 14.3% and 0.2%. Cancer rates for patients with a family or personal operation history, with cancer history and with no family/operation/cancer history were 0%, 0.1% and 0.2%, respectively. Our results indicate that the cancer detection rate and PPV for US were too low to recommend routine axillary scanning including screening breast US in patients with negative mammography and subsequent breast US, especially with no history of any cancers.

Original language	English
Pages (from-to)	71-77
Number of pages	7
Journal	Ultrasound in Medicine and Biology
Volume	44
Issue number	1
DOIs	https://doi.org/10.1016/j.ultrasmedbio.2017.08.1888
Publication status	Published - 2018 Jan

Bibliographical note

Funding Information:
This study was supported by the Basic Science Research Program of the National Research Foundation of Korea funded by the Ministry of Science, ICT& Future Planning, Republic of Korea (grant 2013 R1 A1 A3013165 and 2017 R1 A2 B4010407 ); by a faculty research grant of Yonsei University College of Medicine for 2015(6-2015-0050) ; and by Research Institute of Radiologic Science, Yonsei University College of Medicine. The funding institutions had no role in study design, data collection and analysis, decision to publish or preparation of the manuscript. The institutional review board approved this retrospective observational study (IRB No.4-2016-0125).

Publisher Copyright:
© 2018 World Federation for Ultrasound in Medicine and Biology

All Science Journal Classification (ASJC) codes

Radiological and Ultrasound Technology
Biophysics
Acoustics and Ultrasonics

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.ultrasmedbio.2017.08.1888

Cite this

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title = "Necessity of Axillary Scanning After Negative Finding on Both Mammography and Subsequent Breast Ultrasound",

abstract = "The purpose of our study was to assess the cancer detection rate and positive predictive value (PPV) for incidentally detected abnormal axillary lymph nodes with negative mammography and subsequent breast ultrasound (US). We included 7039 screened patients (mean age, 52 y) from January 2012 to March 2015 with negative mammography and subsequent breast US results. In two patients with positive lymph nodes, neither were from breast malignancy. The calculated cancer detection rate, PPV for biopsy and axillary biopsy rate was 0.3 per 1000 axillary US, 14.3% and 0.2%. Cancer rates for patients with a family or personal operation history, with cancer history and with no family/operation/cancer history were 0%, 0.1% and 0.2%, respectively. Our results indicate that the cancer detection rate and PPV for US were too low to recommend routine axillary scanning including screening breast US in patients with negative mammography and subsequent breast US, especially with no history of any cancers.",

author = "Inyoung Youn and Yoon, {Jung Hyun} and Youk, {Ji Hyun} and Moon, {Hee Jung} and Kim, {Min Jung} and Kim, {Eun Kyung} and You, {Jai Kyung}",

note = "Funding Information: This study was supported by the Basic Science Research Program of the National Research Foundation of Korea funded by the Ministry of Science, ICT& Future Planning, Republic of Korea (grant 2013 R1 A1 A3013165 and 2017 R1 A2 B4010407 ); by a faculty research grant of Yonsei University College of Medicine for 2015(6-2015-0050) ; and by Research Institute of Radiologic Science, Yonsei University College of Medicine. The funding institutions had no role in study design, data collection and analysis, decision to publish or preparation of the manuscript. The institutional review board approved this retrospective observational study (IRB No.4-2016-0125). Publisher Copyright: {\textcopyright} 2018 World Federation for Ultrasound in Medicine and Biology",

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AU - Youk, Ji Hyun

AU - Moon, Hee Jung

AU - Kim, Min Jung

AU - Kim, Eun Kyung

AU - You, Jai Kyung

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PY - 2018/1

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N2 - The purpose of our study was to assess the cancer detection rate and positive predictive value (PPV) for incidentally detected abnormal axillary lymph nodes with negative mammography and subsequent breast ultrasound (US). We included 7039 screened patients (mean age, 52 y) from January 2012 to March 2015 with negative mammography and subsequent breast US results. In two patients with positive lymph nodes, neither were from breast malignancy. The calculated cancer detection rate, PPV for biopsy and axillary biopsy rate was 0.3 per 1000 axillary US, 14.3% and 0.2%. Cancer rates for patients with a family or personal operation history, with cancer history and with no family/operation/cancer history were 0%, 0.1% and 0.2%, respectively. Our results indicate that the cancer detection rate and PPV for US were too low to recommend routine axillary scanning including screening breast US in patients with negative mammography and subsequent breast US, especially with no history of any cancers.

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Necessity of Axillary Scanning After Negative Finding on Both Mammography and Subsequent Breast Ultrasound

Abstract

Bibliographical note

All Science Journal Classification (ASJC) codes

UN SDGs

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