Myocardial enhancement pattern in patients with acute myocardial infarction on two-phase contrast-enhanced ECG-gated multidetector-row computed tomography

S. M. Ko, J. B. Seo, M. K. Hong, K. H. Do, S. H. Lee, J. S. Lee, J. W. Song, S. J. Park, S. W. Park, T. H. Lim

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Abstract

AIM: To evaluate the myocardial enhancement pattern of the left ventricle on two-phase contrast-enhanced electrocardiogram (ECG)-gated multidetector computed tomography (MDCT) images in patients with acute myocardial infarction (AMI). METHODS: Two-phase contrast-enhanced ECG-gated MDCT examinations were performed in 16 patients with AMI. The presence, location and pattern of myocardial enhancement were evaluated. MDCT findings were compared with the catheter angiographic results. RESULTS: Subendocardial (n=9) or transmural (n=6) area of early perfusion defects of the myocardium was detected in 15 of 16 patients (94%) on early-phase CT images. Variable delayed myocardial enhancement patterns on late-phase CT images were observed in 12 patients (75%): (1) subendocardial residual perfusion defect and subepicardial late enhancement (n=6); (2) transmural late enhancement (n=1); (3) isolated subendocardial late enhancement (n=1); and (4) isolated subendocardial residual perfusion defect (n=2). On catheter angiography, 14 of 15 corresponding coronary arteries showed significant stenosis. CONCLUSION: Variable abnormal myocardial enhancement pattern was seen on two-phase, contrast-enhanced ECG-gated MDCT in patients with AMI. Assessment of myocardial attenuation on CT angiography gives additional information of the location and extent of infarction.

Original languageEnglish
Pages (from-to)417-422
Number of pages6
JournalClinical Radiology
Volume61
Issue number5
DOIs
Publication statusPublished - 2006 May

Bibliographical note

Funding Information:
This study was supported by a grant (2003-337) from the Asan Institute for Life Science, Seoul, South Korea.

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

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