Multiple biological properties of macelignan and its pharmacological implications

Saswati Paul, Jae Kwan Hwang, Hahn Young Kim, Won Kyung Jeon, Chihye Chung, Jung Soo Han

Research output: Contribution to journalReview articlepeer-review

24 Citations (Scopus)


Macelignan found in the nutmeg mace of Myristica fragrans obtains increasing attention as a new avenue in treating various diseases. Macelignan has been shown to possess a spectrum of pharmacological activities, including anti-bacterial, anti-inflammatory, anti-cancer, anti-diabetes, and hepatoprotective activities; recently, it has also been shown to have neuroprotective activities. This review summarizes the current research on the biological effects of macelignan derived from M. fragrans, with emphasis on the importance in understanding and treating complex diseases such as cancer and Alzheimer's disease.

Original languageEnglish
Pages (from-to)264-272
Number of pages9
JournalArchives of pharmacal research
Issue number3
Publication statusPublished - 2013 Mar

Bibliographical note

Funding Information:
Acknowledgments This paper was supported by Konkuk University research support program (2011)

All Science Journal Classification (ASJC) codes

  • Molecular Medicine
  • Drug Discovery
  • Organic Chemistry


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