Multiphoton luminescent graphene quantum dots for in vivo tracking of human adipose-derived stem cells

Jin Kim; Sung Ho Song; Yoonhee Jin; Hyun Ji Park; Hyewon Yoon; Seokwoo Jeon; Seung Woo Cho

doi:10.1039/c6nr02143c

Multiphoton luminescent graphene quantum dots for in vivo tracking of human adipose-derived stem cells

Jin Kim, Sung Ho Song, Yoonhee Jin, Hyun Ji Park, Hyewon Yoon, Seokwoo Jeon, Seung Woo Cho

Research output: Contribution to journal › Article › peer-review

35 Citations (Scopus)

Abstract

The applicability of graphene quantum dots (GQDs) for the in vitro and in vivo live imaging and tracking of different types of human stem cells is investigated. GQDs synthesized by the modified graphite intercalated compound method show efficient cellular uptake with improved biocompatibility and highly sensitive optical properties, indicating their feasibility as a bio-imaging probe for stem cell therapy.

Original language	English
Pages (from-to)	8512-8519
Number of pages	8
Journal	Nanoscale
Volume	8
Issue number	16
DOIs	https://doi.org/10.1039/c6nr02143c
Publication status	Published - 2016 Apr 28

Bibliographical note

Funding Information:
This work was supported by grants (HI13C1479 and HI14C1588) from the Korea Health Technology R&D Project funded by the Ministry of Health and Welfare, Republic of Korea. This research was also supported by Nano-Material Technology Development Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Science, ICT and Future Planning (MSIP) (2012M3A7B4049807) and by the Center for Advanced Soft-Electronics funded by the MSIP as Global Frontier (CASE-2013M3A6A5073173).

Publisher Copyright:
© The Royal Society of Chemistry 2016.

All Science Journal Classification (ASJC) codes

Materials Science(all)

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10.1039/c6nr02143c

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abstract = "The applicability of graphene quantum dots (GQDs) for the in vitro and in vivo live imaging and tracking of different types of human stem cells is investigated. GQDs synthesized by the modified graphite intercalated compound method show efficient cellular uptake with improved biocompatibility and highly sensitive optical properties, indicating their feasibility as a bio-imaging probe for stem cell therapy.",

author = "Jin Kim and Song, {Sung Ho} and Yoonhee Jin and Park, {Hyun Ji} and Hyewon Yoon and Seokwoo Jeon and Cho, {Seung Woo}",

note = "Funding Information: This work was supported by grants (HI13C1479 and HI14C1588) from the Korea Health Technology R&D Project funded by the Ministry of Health and Welfare, Republic of Korea. This research was also supported by Nano-Material Technology Development Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Science, ICT and Future Planning (MSIP) (2012M3A7B4049807) and by the Center for Advanced Soft-Electronics funded by the MSIP as Global Frontier (CASE-2013M3A6A5073173). Publisher Copyright: {\textcopyright} The Royal Society of Chemistry 2016.",

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AU - Song, Sung Ho

AU - Jin, Yoonhee

AU - Park, Hyun Ji

AU - Yoon, Hyewon

AU - Jeon, Seokwoo

AU - Cho, Seung Woo

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PY - 2016/4/28

Y1 - 2016/4/28

N2 - The applicability of graphene quantum dots (GQDs) for the in vitro and in vivo live imaging and tracking of different types of human stem cells is investigated. GQDs synthesized by the modified graphite intercalated compound method show efficient cellular uptake with improved biocompatibility and highly sensitive optical properties, indicating their feasibility as a bio-imaging probe for stem cell therapy.

AB - The applicability of graphene quantum dots (GQDs) for the in vitro and in vivo live imaging and tracking of different types of human stem cells is investigated. GQDs synthesized by the modified graphite intercalated compound method show efficient cellular uptake with improved biocompatibility and highly sensitive optical properties, indicating their feasibility as a bio-imaging probe for stem cell therapy.

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Multiphoton luminescent graphene quantum dots for in vivo tracking of human adipose-derived stem cells

Abstract

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