Multinucleation of koilocytes is actually multilobation

N. H. Cho, S. Kang, S. Hong, G. B. Jeong, I. W. Choi, H. J. Choi, H. K. Choi

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)


In order to clarify the complete cytomorphology of cytopathic changes as a consequence of human papillomavirus (HPV) infection, we performed three-dimensional (3D) reconstruction from confocal fluorescent images. After confirming 22 HPV types using a DNA chip, we performed 3D confocal image restoration in human uterine cervical swab samples and corresponding tumor tissues. On restoration of 3D confocal images, the multinucleated feature of koilocytes was revealed to be multilobation of a single nucleus, as opposed to true multinucleation.

Original languageEnglish
Pages (from-to)686-689
Number of pages4
JournalInternational Journal of Gynecological Cancer
Issue number2
Publication statusPublished - 2006 Mar

All Science Journal Classification (ASJC) codes

  • Oncology
  • Obstetrics and Gynaecology


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