Multicenter prospective comparative study of robotic versus laparoscopic gastrectomy for gastric adenocarcinoma

Hyoung Il Kim, Sang Uk Han, Han Kwang Yang, Young Woo Kim, Hyuk Joon Lee, Keun Won Ryu, Joong Min Park, Ji Yeong An, Min Chan Kim, Sungsoo Park, Kyo Young Song, Sung Jin Oh, Seong Ho Kong, Byoung Jo Suh, Dae Hyun Yang, Tae Kyung Ha, Youn Nam Kim, Woo Jin Hyung

Research output: Contribution to journalArticlepeer-review

209 Citations (Scopus)


Objective: To compare short-term surgical outcomes including financial cost of robotic and laparoscopic gastrectomy. Background: Despite a lack of supporting evidence, robotic surgery has been increasingly adopted as a minimally invasive modality for the treatment of gastric cancer because of its assumed technical superiority over conventional laparoscopy. Methods: A prospective, multicenter comparative study was conducted. Patients were matched according to the surgeon, extent of gastric resection, and sex. The primary endpoint was morbidity and mortality. Outcomes were analyzed on an intention-to-treat and per-protocol basis. Results: A total of 434 patients were enrolled for treatment with either robotic (n=223) or laparoscopic (n=211) gastrectomy for intention-to-treat analysis, and a total of 370 patients (n=185 per treatment) were compared in per-protocol analysis. Results were similar between both analyses. In perprotocol analysis, both group s showed similar overall complication rates (robotic=11.9% vs laparoscopic=10.3%) and major complication rates (robotic=1.1% vs laparoscopic=1.1%) with no operative mortality in either group. Patients treated with robotic surgery showed significantly longer operative time (robotic=221 minutes vs laparoscopic=178 minutes; P<0.001) and significantly higher total costs (robotic=US$13,432 vs laparoscopic=US$8090; P<0.001), compared with those who underwent laparoscopic gastrectomy. No significant differences between groups were noted in estimated blood loss, rates of open conversion, diet build-up, or length of hospital stay. Conclusions: The use of robotic systems is assumed to provide a technically superior operative environment for minimally invasive surgery. However, our analysis of perioperative surgical outcomes indicated that robotic gastrectomy is not superior to laparoscopic gastrectomy. Clinical trials identification: NCT01309256.

Original languageEnglish
Pages (from-to)103-109
Number of pages7
JournalAnnals of surgery
Issue number1
Publication statusPublished - 2016

Bibliographical note

Publisher Copyright:
© Copyright 2015 Wolters Kluwer Health, Inc. All rights reserved.

All Science Journal Classification (ASJC) codes

  • Surgery


Dive into the research topics of 'Multicenter prospective comparative study of robotic versus laparoscopic gastrectomy for gastric adenocarcinoma'. Together they form a unique fingerprint.

Cite this