TY - JOUR
T1 - Molecular testing of lymphoproliferative disorders
T2 - Current status and perspectives
AU - The Hematopathology Study Group of the Korean Society of Pathologists
AU - The Molecular Pathology Study Group of Korean Society of Pathologists
AU - Jeon, Yoon Kyung
AU - Yoon, Sun Och
AU - Paik, Jin Ho
AU - Kim, Young A.
AU - Shin, Bong Kyung
AU - Kim, Hyun Jung
AU - Cha, Hee Jeong
AU - Kim, Ji Eun
AU - Huh, Jooryung
AU - Ko, Young Hyeh
N1 - Publisher Copyright:
© 2017 The Korean Society of Pathologists/The Korean Society for Cytopathology.
PY - 2017/5/1
Y1 - 2017/5/1
N2 - Molecular pathologic testing plays an important role for the diagnosis, prognostication and decision of treatment strategy in lymphoproliferative disease. Here, we briefly review the molecular tests currently used for lymphoproliferative disease and those which will be implicated in clinical practice in the near future. Specifically, this guideline addresses the clonality test for B- and T-cell proliferative lesions, molecular cytogenetic tests for malignant lymphoma, determination of cellof- origin in diffuse large B-cell lymphoma, and molecular genetic alterations incorporated in the 2016 revision of the World Health Organization classification of lymphoid neoplasms. Finally, a new perspective on the next-generation sequencing for diagnostic, prognostic, and therapeutic purpose in malignant lymphoma will be summarized.
AB - Molecular pathologic testing plays an important role for the diagnosis, prognostication and decision of treatment strategy in lymphoproliferative disease. Here, we briefly review the molecular tests currently used for lymphoproliferative disease and those which will be implicated in clinical practice in the near future. Specifically, this guideline addresses the clonality test for B- and T-cell proliferative lesions, molecular cytogenetic tests for malignant lymphoma, determination of cellof- origin in diffuse large B-cell lymphoma, and molecular genetic alterations incorporated in the 2016 revision of the World Health Organization classification of lymphoid neoplasms. Finally, a new perspective on the next-generation sequencing for diagnostic, prognostic, and therapeutic purpose in malignant lymphoma will be summarized.
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U2 - 10.4132/jptm.2017.04.09
DO - 10.4132/jptm.2017.04.09
M3 - Review article
AN - SCOPUS:85019860681
SN - 2383-7837
VL - 51
SP - 224
EP - 241
JO - Journal of Pathology and Translational Medicine
JF - Journal of Pathology and Translational Medicine
IS - 3
ER -