Microfluidic components and bio-reactors for miniaturized bio-chip applications

Kwang Seok Yun, Euisik Yoon

Research output: Contribution to journalArticlepeer-review

15 Citations (Scopus)


In this paper miniaturized disposable micro/nanofluidic components applicable to bio chip, chemical analyzer and biomedical monitoring system, such as blood analysis, micro dosing system and cell experiment, etc are reported. This system includes various microfluidic components including a micropump, micromixer, DNA purification chip and single-cell assay chip. For low voltage and low power operation, a surface tension-driven micropump is presented, as well as a micromixer, which was implemented using MEMS technology, for efficient liquid mixing is also introduced. As bio-reactors, DNA purification and single-cell assay devices, for the extraction of pure DNA from liquid mixture or blood and for cellular engineering or high-throughput screening, respectively, are presented.

Original languageEnglish
Pages (from-to)86-92
Number of pages7
JournalBiotechnology and Bioprocess Engineering
Issue number2
Publication statusPublished - 2004

Bibliographical note

Funding Information:
ported by the NRL program from the Ministry of Science and Technology, the KOSEF through the MICROS center at KAIST and the project of “Development of micro optical and ther-mofluidic devices with high functionality” from the Ministry of Commerce, Industry and Energy of Korea.

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Bioengineering
  • Applied Microbiology and Biotechnology
  • Biomedical Engineering


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