Microbial Modulation in Inflammatory Bowel Diseases

Jongwook Yu, Jae Hee Cheon

Research output: Contribution to journalReview articlepeer-review

1 Citation (Scopus)


Gut dysbiosis is one of prominent features in inflammatory bowel diseases (IBDs) which are of an unknown etiology. Although the cause-and-effect relationship between IBD and gut dysbiosis remains to be elucidated, one area of research has focused on the management of IBD by modulating and correcting gut dysbiosis. The use of antibiotics, probiotics either with or without prebiotics, and fecal microbiota transplantation from healthy donors are representative methods for modulating the intestinal microbiota ecosystem. The gut microbiota is not a simple assembly of bacteria, fungi, and viruses, but a complex organ-like community system composed of numerous kinds of microorganisms. Thus, studies on specific changes in the gut microbiota depending on which treatment option is applied are very limited. Here, we review previous studies on microbial modulation as a therapeutic option for IBD and its significance in the pathogenesis of IBD.

Original languageEnglish
Article numbere44
JournalImmune Network
Issue number6
Publication statusPublished - 2022 Dec 1

Bibliographical note

Publisher Copyright:
© 2022. The Korean Association of Immunologists.

All Science Journal Classification (ASJC) codes

  • Immunology and Allergy
  • Immunology
  • Infectious Diseases


Dive into the research topics of 'Microbial Modulation in Inflammatory Bowel Diseases'. Together they form a unique fingerprint.

Cite this