TY - GEN
T1 - Manipulation of phospholiposome in microfluidic channel using lorentz force
AU - Son, Oh Taek
AU - Park, Jong Ho
AU - Lee, Chang Geun
AU - Lee, Changhoon
AU - Jung, Hyo Il
PY - 2007
Y1 - 2007
N2 - Manipulation of biomolecules in microfluidic channel is very important in biochip technology. Here, we report a label-free handling method of biomolecules using magneto-hydrodynamic (MHD) force. Phospholiposome was used in our experiments as it contains charged phospholipids and is spherical. Its mobility in microfluidic channel was analyzed by CFD (Fluent 6.2) and experiments were performed thereafter. The trajectory of the liposome was changed by the influence of external magnetic field. The factors affecting the flow of the liposome are thought to be charge density on the surface of the liposome and the Lorentz force. Results of our work are expected to be applied to manipulate various biomolecules containing electrostatic charges in microfluidic channel.
AB - Manipulation of biomolecules in microfluidic channel is very important in biochip technology. Here, we report a label-free handling method of biomolecules using magneto-hydrodynamic (MHD) force. Phospholiposome was used in our experiments as it contains charged phospholipids and is spherical. Its mobility in microfluidic channel was analyzed by CFD (Fluent 6.2) and experiments were performed thereafter. The trajectory of the liposome was changed by the influence of external magnetic field. The factors affecting the flow of the liposome are thought to be charge density on the surface of the liposome and the Lorentz force. Results of our work are expected to be applied to manipulate various biomolecules containing electrostatic charges in microfluidic channel.
UR - http://www.scopus.com/inward/record.url?scp=34548132001&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=34548132001&partnerID=8YFLogxK
U2 - 10.1109/NEMS.2007.352079
DO - 10.1109/NEMS.2007.352079
M3 - Conference contribution
AN - SCOPUS:34548132001
SN - 1424406102
SN - 9781424406104
T3 - Proceedings of the 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2007
SP - 552
EP - 555
BT - Proceedings of the 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2007
T2 - 2007 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2007
Y2 - 16 January 2007 through 19 January 2007
ER -