Magnetic nanoclusters for ultrasensitive magnetophoretic assays

Zongwen Jin; Young Ki Hahn; Eunkeu Oh; Young Pil Kim; Je Kyun Park; Seung Ho Moon; Jung Tak Jang; Jinwoo Cheon; Hak Sung Kim

doi:10.1002/smll.200900311

Magnetic nanoclusters for ultrasensitive magnetophoretic assays

Zongwen Jin, Young Ki Hahn, Eunkeu Oh, Young Pil Kim, Je Kyun Park, Seung Ho Moon, Jung Tak Jang, Jinwoo Cheon, Hak Sung Kim

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

11 Citations (Scopus)

Abstract

Magnetic nanoclusters (MNCs) are developed and used for an ultrasensitive magnetophoretic assay system. Prostate-specific antigen (PSA) is used as a target analyte (see image). The deflection velocity of a microbead is well correlated with the PSA concentration, with a detection limit of 45 fg mL -1 , and this value is three orders of magnitude higher than conventional ELISA. The developed assay format is expected to be effectively applied to the detection of a target analyte with low abundance.

Original language	English
Pages (from-to)	2243-2246
Number of pages	4
Journal	Small
Volume	5
Issue number	20
DOIs	https://doi.org/10.1002/smll.200900311
Publication status	Published - 2009 Oct 16

All Science Journal Classification (ASJC) codes

Biotechnology
Biomaterials
Chemistry(all)
Materials Science(all)

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10.1002/smll.200900311

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author = "Zongwen Jin and Hahn, {Young Ki} and Eunkeu Oh and Kim, {Young Pil} and Park, {Je Kyun} and Moon, {Seung Ho} and Jang, {Jung Tak} and Jinwoo Cheon and Kim, {Hak Sung}",

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AU - Jin, Zongwen

AU - Hahn, Young Ki

AU - Oh, Eunkeu

AU - Kim, Young Pil

AU - Park, Je Kyun

AU - Moon, Seung Ho

AU - Jang, Jung Tak

AU - Cheon, Jinwoo

AU - Kim, Hak Sung

PY - 2009/10/16

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Magnetic nanoclusters for ultrasensitive magnetophoretic assays

Abstract

All Science Journal Classification (ASJC) codes

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