Left Atrial Volume Index Predicts Recurrence of Stroke in Patients with Nonsustained Atrial Tachycardia

Hyemoon Chung, Boyoung Joung, Kyung Yul Lee, Jae Sun Uhm, Hui Nam Pak, Moon Hyoung Lee, Jong Youn Kim

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)


Background Nonsustained atrial tachycardia (NSAT) is known to appear more frequently in patients with paroxysmal atrial fibrillation (AF). Enlarged left atrium (LA) is considered to be an independent risk factor for newly diagnosed AF. Methods We investigated the risk factors for predicting the stroke recurrence in NSAT patients. In total, 252 patients (114 women, mean 70 ± 11 years) with acute ischemic stroke and documented NSAT in 24-hour Holter monitoring were enrolled and followed. All patients underwent echo-Doppler evaluations. Results During a mean follow-up period of 35 ± 31 months, the stroke recurrence rate was 11.1% (28 of 252). The patients with recurrence (n = 28) had higher left atrium volume index (LAVI, P <.001) and higher E/e' (P =.028) compared with those without recurrence (n = 224). On the Kaplan-Meier survival analysis, stroke recurrence rate was significantly higher in patients with enlarged LA (LAVI >28 mm3/m2; P <.001 by the log-rank test), and it remained significant in multivariate analysis (hazard ratio, 1.154; 95% confidence interval [CI], 1.099-1.212, P <.001). Conclusions In patients with acute ischemic stroke and NSAT, enlarged LA predicts an increased risk of stroke recurrence. This study supports the necessity of prolonged rhythm monitoring in stroke patients with NSAT and enlarged LA to detect undiagnosed AF and consequently considering anticoagulation therapy.

Original languageEnglish
Pages (from-to)2408-2415
Number of pages8
JournalJournal of Stroke and Cerebrovascular Diseases
Issue number10
Publication statusPublished - 2015 Oct 1

Bibliographical note

Publisher Copyright:
© 2015 National Stroke Association.

All Science Journal Classification (ASJC) codes

  • Surgery
  • Rehabilitation
  • Clinical Neurology
  • Cardiology and Cardiovascular Medicine


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