Layer-by-layer assembly of multilayer films for controlled drug release

Daheui Choi, Jinkee Hong

Research output: Contribution to journalReview articlepeer-review

37 Citations (Scopus)


Drug efficacy has been improved using various methods that enhance targeting, decrease toxicity, and facilitate timely and sustained drug release. To achieve these properties, various drug loading and release platforms have been developed. Layer-by-layer (LbL) self-assembly is widely used to generate controlled and sustained drug release LbL multilayer films because it allows desired functions and structures to be obtained through a simple procedure. In this review article, we highlight controlled drug release from LbL self-assembling films with diverse release kinetics, particularly with regard to mechanisms of drug release.

Original languageEnglish
Pages (from-to)79-87
Number of pages9
JournalArchives of pharmacal research
Issue number1
Publication statusPublished - 2014 Jan

Bibliographical note

Funding Information:
Acknowledgments This research was supported by the Chung-Ang University Excellent Student Scholarship in 2013 and National Research Foundation of Korea (NRF) funded by the Ministry of Science, ICT and Future Planning (NRF-2012M3A9C6050104).

All Science Journal Classification (ASJC) codes

  • Molecular Medicine
  • Drug Discovery
  • Organic Chemistry


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