Intravesical bacillus Calmette–Guérin-induced myopathy presenting as rhabdomyolysis: a case report

Chae Hun Lee; Byeong Joo Choi; Jung Hun Kim; Tae Woong Yang; Gi Jeong Kim; Ha Young Shin; Se Hoon Kim; Seung Woo Kim

doi:10.12701/jyms.2022.00850

Intravesical bacillus Calmette–Guérin-induced myopathy presenting as rhabdomyolysis: a case report

Chae Hun Lee, Byeong Joo Choi, Jung Hun Kim, Tae Woong Yang, Gi Jeong Kim, Ha Young Shin, Se Hoon Kim, Seung Woo Kim

Department of Pathology

Research output: Contribution to journal › Article › peer-review

Abstract

Intravesical bacillus Calmette–Guérin (BCG) instillation is an adjuvant treatment for non–muscle-invasive urinary bladder cancer. Al-though most complications associated with BCG immunotherapy are mild and self-limiting, rare albeit serious complications have been reported. Only a few cases of BCG-related rhabdomyolysis have been reported. In this study, we present the case of a 72-year-old woman who developed severe weakness and hyperCKemia following intravesical BCG instillation. A muscle biopsy was performed, and a diagnosis of drug-induced myopathy was made.

Original language	English
Pages (from-to)	430-434
Number of pages	5
Journal	Journal of Yeungnam Medical Science
Volume	40
Issue number	4
DOIs	https://doi.org/10.12701/jyms.2022.00850
Publication status	Published - 2023 Oct

Bibliographical note

Publisher Copyright:
© 2023 Yeungnam University College of Medicine, Yeungnam University Institute of Medical Science.

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.12701/jyms.2022.00850

Cite this

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title = "Intravesical bacillus Calmette–Gu{\'e}rin-induced myopathy presenting as rhabdomyolysis: a case report",

abstract = "Intravesical bacillus Calmette–Gu{\'e}rin (BCG) instillation is an adjuvant treatment for non–muscle-invasive urinary bladder cancer. Al-though most complications associated with BCG immunotherapy are mild and self-limiting, rare albeit serious complications have been reported. Only a few cases of BCG-related rhabdomyolysis have been reported. In this study, we present the case of a 72-year-old woman who developed severe weakness and hyperCKemia following intravesical BCG instillation. A muscle biopsy was performed, and a diagnosis of drug-induced myopathy was made.",

keywords = "BCG vaccine, Intravesical administration, Muscular diseases, Rhabdomyolysis",

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doi = "10.12701/jyms.2022.00850",

language = "English",

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AU - Lee, Chae Hun

AU - Choi, Byeong Joo

AU - Kim, Jung Hun

AU - Yang, Tae Woong

AU - Kim, Gi Jeong

AU - Shin, Ha Young

AU - Kim, Se Hoon

AU - Kim, Seung Woo

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N2 - Intravesical bacillus Calmette–Guérin (BCG) instillation is an adjuvant treatment for non–muscle-invasive urinary bladder cancer. Al-though most complications associated with BCG immunotherapy are mild and self-limiting, rare albeit serious complications have been reported. Only a few cases of BCG-related rhabdomyolysis have been reported. In this study, we present the case of a 72-year-old woman who developed severe weakness and hyperCKemia following intravesical BCG instillation. A muscle biopsy was performed, and a diagnosis of drug-induced myopathy was made.

AB - Intravesical bacillus Calmette–Guérin (BCG) instillation is an adjuvant treatment for non–muscle-invasive urinary bladder cancer. Al-though most complications associated with BCG immunotherapy are mild and self-limiting, rare albeit serious complications have been reported. Only a few cases of BCG-related rhabdomyolysis have been reported. In this study, we present the case of a 72-year-old woman who developed severe weakness and hyperCKemia following intravesical BCG instillation. A muscle biopsy was performed, and a diagnosis of drug-induced myopathy was made.

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KW - Muscular diseases

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Intravesical bacillus Calmette–Guérin-induced myopathy presenting as rhabdomyolysis: a case report

Abstract

Bibliographical note

All Science Journal Classification (ASJC) codes

UN SDGs

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