Intestinal fluke Metagonimus yokogawai infection increases probiotic Lactobacillus in mouse cecum

Ju Yeong Kim; Eun Min Kim; Myung hee Yi; Jinyoung Lee; Seogwon Lee; Younjee Hwang; Dongeun Yong; Woon Mok Sohn; Tai Soon Yong

doi:10.1016/j.exppara.2018.08.002

Intestinal fluke Metagonimus yokogawai infection increases probiotic Lactobacillus in mouse cecum

Ju Yeong Kim, Eun Min Kim, Myung hee Yi, Jinyoung Lee, Seogwon Lee, Younjee Hwang, Dongeun Yong, Woon Mok Sohn, Tai Soon Yong

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

Abstract

Helminth infection can alleviate immune-mediated disorders such as allergies and autoimmune diseases, by altering the gut microbiome. However, changes in gut microbiome due to intestinal trematodes remain unelucidated. Here, we evaluated the changes in the gut microbiome of ICR mice infected with Metagonimus yokogawai, a hypo-virulent intestinal trematode. Four weeks after infection, mouse cecal content was analyzed by 16S rRNA amplicon analysis. Although there was no apparent difference in species richness and diversity, the microbiome composition was different in the infected and control groups. Furthermore, several Lactobacillus species with known immunomodulatory role in immune-mediated diseases were increased in the infected group.

Original language	English
Pages (from-to)	45-50
Number of pages	6
Journal	Experimental Parasitology
Volume	193
DOIs	https://doi.org/10.1016/j.exppara.2018.08.002
Publication status	Published - 2018 Oct

Bibliographical note

Funding Information:
This study was supported by a National Research Foundation of Korea (NRF) grant funded by the Korean Government (MEST; number NRF-2016R1A2B4016194 and 2011-0012166).

Funding Information:
This study was supported by a National Research Foundation of Korea (NRF) grant funded by the Korean Government (MEST; number NRF- 2016R1A2B4016194 and 2011-0012166 ).

Publisher Copyright:
© 2018 Elsevier Inc.

All Science Journal Classification (ASJC) codes

Parasitology
Immunology
Infectious Diseases

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/j.exppara.2018.08.002

Cite this

@article{b4cb0ce506744badbebb8086c65d3c36,

title = "Intestinal fluke Metagonimus yokogawai infection increases probiotic Lactobacillus in mouse cecum",

abstract = "Helminth infection can alleviate immune-mediated disorders such as allergies and autoimmune diseases, by altering the gut microbiome. However, changes in gut microbiome due to intestinal trematodes remain unelucidated. Here, we evaluated the changes in the gut microbiome of ICR mice infected with Metagonimus yokogawai, a hypo-virulent intestinal trematode. Four weeks after infection, mouse cecal content was analyzed by 16S rRNA amplicon analysis. Although there was no apparent difference in species richness and diversity, the microbiome composition was different in the infected and control groups. Furthermore, several Lactobacillus species with known immunomodulatory role in immune-mediated diseases were increased in the infected group.",

author = "Kim, {Ju Yeong} and Kim, {Eun Min} and Yi, {Myung hee} and Jinyoung Lee and Seogwon Lee and Younjee Hwang and Dongeun Yong and Sohn, {Woon Mok} and Yong, {Tai Soon}",

note = "Funding Information: This study was supported by a National Research Foundation of Korea (NRF) grant funded by the Korean Government (MEST; number NRF-2016R1A2B4016194 and 2011-0012166). Funding Information: This study was supported by a National Research Foundation of Korea (NRF) grant funded by the Korean Government (MEST; number NRF- 2016R1A2B4016194 and 2011-0012166 ). Publisher Copyright: {\textcopyright} 2018 Elsevier Inc.",

year = "2018",

month = oct,

doi = "10.1016/j.exppara.2018.08.002",

language = "English",

volume = "193",

pages = "45--50",

journal = "Experimental Parasitology",

issn = "0014-4894",

publisher = "Academic Press Inc.",

}

TY - JOUR

T1 - Intestinal fluke Metagonimus yokogawai infection increases probiotic Lactobacillus in mouse cecum

AU - Kim, Ju Yeong

AU - Kim, Eun Min

AU - Yi, Myung hee

AU - Lee, Jinyoung

AU - Lee, Seogwon

AU - Hwang, Younjee

AU - Yong, Dongeun

AU - Sohn, Woon Mok

AU - Yong, Tai Soon

N1 - Funding Information: This study was supported by a National Research Foundation of Korea (NRF) grant funded by the Korean Government (MEST; number NRF-2016R1A2B4016194 and 2011-0012166). Funding Information: This study was supported by a National Research Foundation of Korea (NRF) grant funded by the Korean Government (MEST; number NRF- 2016R1A2B4016194 and 2011-0012166 ). Publisher Copyright: © 2018 Elsevier Inc.

PY - 2018/10

Y1 - 2018/10

N2 - Helminth infection can alleviate immune-mediated disorders such as allergies and autoimmune diseases, by altering the gut microbiome. However, changes in gut microbiome due to intestinal trematodes remain unelucidated. Here, we evaluated the changes in the gut microbiome of ICR mice infected with Metagonimus yokogawai, a hypo-virulent intestinal trematode. Four weeks after infection, mouse cecal content was analyzed by 16S rRNA amplicon analysis. Although there was no apparent difference in species richness and diversity, the microbiome composition was different in the infected and control groups. Furthermore, several Lactobacillus species with known immunomodulatory role in immune-mediated diseases were increased in the infected group.

AB - Helminth infection can alleviate immune-mediated disorders such as allergies and autoimmune diseases, by altering the gut microbiome. However, changes in gut microbiome due to intestinal trematodes remain unelucidated. Here, we evaluated the changes in the gut microbiome of ICR mice infected with Metagonimus yokogawai, a hypo-virulent intestinal trematode. Four weeks after infection, mouse cecal content was analyzed by 16S rRNA amplicon analysis. Although there was no apparent difference in species richness and diversity, the microbiome composition was different in the infected and control groups. Furthermore, several Lactobacillus species with known immunomodulatory role in immune-mediated diseases were increased in the infected group.

UR - http://www.scopus.com/inward/record.url?scp=85053168898&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85053168898&partnerID=8YFLogxK

U2 - 10.1016/j.exppara.2018.08.002

DO - 10.1016/j.exppara.2018.08.002

M3 - Article

C2 - 30149004

AN - SCOPUS:85053168898

SN - 0014-4894

VL - 193

SP - 45

EP - 50

JO - Experimental Parasitology

JF - Experimental Parasitology

ER -

Intestinal fluke Metagonimus yokogawai infection increases probiotic Lactobacillus in mouse cecum

Abstract

Bibliographical note

All Science Journal Classification (ASJC) codes

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this