Integrative understanding of immune-metabolic interaction

Seonyoung Im, Hawon Kim, Myunghyun Jeong, Hyeon Yang, Jun Young Hong

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)


Recent studies have revealed that the immune system plays a critical role in various physiological processes beyond its classical pathogen control activity. Even under a sterile condition, various cells and tissues can utilize the immune system to meet a specific demand for proper physiological functions. Particularly, a strong link between immunity and metabolism has been identified. Studies have identified the reciprocal regulation between these two systems. For example, immune signals can regulate metabolism, and metabolism (cellular or systemic) can regulate immunity. In this review, we will summarize recent findings on this reciprocal regulation between immunity and metabolism, and discuss potential biological rules behind this interaction with integrative perspectives.

Original languageEnglish
Pages (from-to)259-266
Number of pages8
JournalBMB reports
Issue number6
Publication statusPublished - 2022

Bibliographical note

Publisher Copyright:
© 2022. by the The Korean Society for Biochemistry and Molecular Biology This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Molecular Biology


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