Inhibitory effects of Saussurea involucrata against melanogenesis of mouse-derived melanocyte cells

Qing Mu; Hyun Jung Choi; Li Fei Wang; Xiao Jin Li; Jae Sung Hwang; Byeong Gon Lee; Jia Ye; Bi Yan Zhang; Yin Jin Sun; Nam Hoon Cho; Sang Jun Lee; Young Chul Sim

doi:10.1080/13880200701574950

Inhibitory effects of Saussurea involucrata against melanogenesis of mouse-derived melanocyte cells

Qing Mu, Hyun Jung Choi, Li Fei Wang, Xiao Jin Li, Jae Sung Hwang, Byeong Gon Lee, Jia Ye, Bi Yan Zhang, Yin Jin Sun, Nam Hoon Cho, Sang Jun Lee, Young Chul Sim

Department of Pathology

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

Extracts and fractions from the aerial parts of herbal materials of Saussurea involucrata Kar et Kir ex Maxim (Compositae) were investigated for their whitening activity against mouse-derived immortalized melanocyte cell line. The extract of wild herbs (FS2) possessed a better inhibition (28.2% growth) against melanin cells than that (46.7%) of cultivated herbs (FS1). The whole extracts and middle-polar partitioning fraction show the inhibitory effects, whereas the water-soluble parts show a poor activity in the same assay.

Original language	English
Pages (from-to)	678-682
Number of pages	5
Journal	Pharmaceutical Biology
Volume	45
Issue number	9
DOIs	https://doi.org/10.1080/13880200701574950
Publication status	Published - 2007 Nov

Bibliographical note

Funding Information:
This work was partially supported by the Undergraduate Student Scientific and Innovation Foundation of the School of Pharmacy, Fudan University in China (no. kc200615).

All Science Journal Classification (ASJC) codes

Molecular Medicine
Pharmacology
Pharmaceutical Science
Drug Discovery
Complementary and alternative medicine

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10.1080/13880200701574950

Cite this

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title = "Inhibitory effects of Saussurea involucrata against melanogenesis of mouse-derived melanocyte cells",

abstract = "Extracts and fractions from the aerial parts of herbal materials of Saussurea involucrata Kar et Kir ex Maxim (Compositae) were investigated for their whitening activity against mouse-derived immortalized melanocyte cell line. The extract of wild herbs (FS2) possessed a better inhibition (28.2% growth) against melanin cells than that (46.7%) of cultivated herbs (FS1). The whole extracts and middle-polar partitioning fraction show the inhibitory effects, whereas the water-soluble parts show a poor activity in the same assay.",

author = "Qing Mu and Choi, {Hyun Jung} and Wang, {Li Fei} and Li, {Xiao Jin} and Hwang, {Jae Sung} and Lee, {Byeong Gon} and Jia Ye and Zhang, {Bi Yan} and Sun, {Yin Jin} and Cho, {Nam Hoon} and Lee, {Sang Jun} and Sim, {Young Chul}",

note = "Funding Information: This work was partially supported by the Undergraduate Student Scientific and Innovation Foundation of the School of Pharmacy, Fudan University in China (no. kc200615).",

year = "2007",

month = nov,

doi = "10.1080/13880200701574950",

language = "English",

volume = "45",

pages = "678--682",

journal = "Pharmaceutical Biology",

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T1 - Inhibitory effects of Saussurea involucrata against melanogenesis of mouse-derived melanocyte cells

AU - Mu, Qing

AU - Choi, Hyun Jung

AU - Wang, Li Fei

AU - Li, Xiao Jin

AU - Hwang, Jae Sung

AU - Lee, Byeong Gon

AU - Ye, Jia

AU - Zhang, Bi Yan

AU - Sun, Yin Jin

AU - Cho, Nam Hoon

AU - Lee, Sang Jun

AU - Sim, Young Chul

N1 - Funding Information: This work was partially supported by the Undergraduate Student Scientific and Innovation Foundation of the School of Pharmacy, Fudan University in China (no. kc200615).

PY - 2007/11

Y1 - 2007/11

N2 - Extracts and fractions from the aerial parts of herbal materials of Saussurea involucrata Kar et Kir ex Maxim (Compositae) were investigated for their whitening activity against mouse-derived immortalized melanocyte cell line. The extract of wild herbs (FS2) possessed a better inhibition (28.2% growth) against melanin cells than that (46.7%) of cultivated herbs (FS1). The whole extracts and middle-polar partitioning fraction show the inhibitory effects, whereas the water-soluble parts show a poor activity in the same assay.

AB - Extracts and fractions from the aerial parts of herbal materials of Saussurea involucrata Kar et Kir ex Maxim (Compositae) were investigated for their whitening activity against mouse-derived immortalized melanocyte cell line. The extract of wild herbs (FS2) possessed a better inhibition (28.2% growth) against melanin cells than that (46.7%) of cultivated herbs (FS1). The whole extracts and middle-polar partitioning fraction show the inhibitory effects, whereas the water-soluble parts show a poor activity in the same assay.

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Inhibitory effects of Saussurea involucrata against melanogenesis of mouse-derived melanocyte cells

Abstract

Bibliographical note

All Science Journal Classification (ASJC) codes

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