Indium-mediated mild and facile method for the synthesis of amides

Dae Hyan Cho, Doo Ok Jang

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29 Citations (Scopus)


Indium-mediated coupling reactions of acyl chlorides and amines for the synthesis of amide bonds are described. The reaction afforded high yields of the desired amides under mild and neutral conditions, and it was applicable also to the preparation of peptides without epimerization.

Original languageEnglish
Pages (from-to)2285-2287
Number of pages3
JournalTetrahedron Letters
Issue number11
Publication statusPublished - 2004 Feb 8

Bibliographical note

Funding Information:
This work was supported by Center for Bioactive Molecular Hybrids at Yonsei University.

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry


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