Increased uptake of AV-1451 in a subacute infarction lesion

Soo Hyun Cho; Hanna Cho; Seongbeom Park; Young Hoon Ryu; Jae Yong Choi; Chul Hyoung Lyoo; Duk L. Na; Sang Won Seo; Hee Jin Kim

doi:10.3349/ymj.2018.59.4.563

Increased uptake of AV-1451 in a subacute infarction lesion

Soo Hyun Cho, Hanna Cho, Seongbeom Park, Young Hoon Ryu, Jae Yong Choi, Chul Hyoung Lyoo, Duk L. Na, Sang Won Seo, Hee Jin Kim

Department of Neurology

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

1₈ F-AV-1451 is a tau PET ligand that has high affinity for paired helical filament tau. However, various off-target bindings unrelated to tau have also been reported. Herein, we report a case of 83-year-old woman, who showed abnormal uptake of AV-1451 that was shown to be subacute infarction. Clinicians should recognize that increased uptake of AV-1451 may be related to stroke.

Original language	English
Pages (from-to)	563-565
Number of pages	3
Journal	Yonsei medical journal
Volume	59
Issue number	4
DOIs	https://doi.org/10.3349/ymj.2018.59.4.563
Publication status	Published - 2018 Jun

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© Yonsei University College of Medicine 2018.

All Science Journal Classification (ASJC) codes

Medicine(all)

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10.3349/ymj.2018.59.4.563

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title = "Increased uptake of AV-1451 in a subacute infarction lesion",

abstract = "18 F-AV-1451 is a tau PET ligand that has high affinity for paired helical filament tau. However, various off-target bindings unrelated to tau have also been reported. Herein, we report a case of 83-year-old woman, who showed abnormal uptake of AV-1451 that was shown to be subacute infarction. Clinicians should recognize that increased uptake of AV-1451 may be related to stroke.",

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AU - Cho, Soo Hyun

AU - Cho, Hanna

AU - Park, Seongbeom

AU - Ryu, Young Hoon

AU - Choi, Jae Yong

AU - Lyoo, Chul Hyoung

AU - Na, Duk L.

AU - Seo, Sang Won

AU - Kim, Hee Jin

PY - 2018/6

Y1 - 2018/6

N2 - 18 F-AV-1451 is a tau PET ligand that has high affinity for paired helical filament tau. However, various off-target bindings unrelated to tau have also been reported. Herein, we report a case of 83-year-old woman, who showed abnormal uptake of AV-1451 that was shown to be subacute infarction. Clinicians should recognize that increased uptake of AV-1451 may be related to stroke.

AB - 18 F-AV-1451 is a tau PET ligand that has high affinity for paired helical filament tau. However, various off-target bindings unrelated to tau have also been reported. Herein, we report a case of 83-year-old woman, who showed abnormal uptake of AV-1451 that was shown to be subacute infarction. Clinicians should recognize that increased uptake of AV-1451 may be related to stroke.

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JO - Yonsei medical journal

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Increased uptake of AV-1451 in a subacute infarction lesion

Abstract

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