Incorporation of cytochrome C with thin calcium phosphate film formed by electron-beam evaporation

Yan Li, In Seop Lee, Fu Zhai Cui, Zeng Lin, Jong Chul Park, Sung Min Chung

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)


Surface properties play a major role to determine the biocompatibility that is the ability of a material to perform with an appropriate host response in a specific application because biomaterials contact and interact with biological systems. Various methods have been studied to improve the surface properties and farther the osseous intergradation of bone implants. Cytochrome C (cyt C) was immobilized on the thin calcium phosphate films formed by electron-beam evaporation in the form of cyt C-apatite composite layer. The newly formed apatite layer was observed by scanning electron microscopy, and X-ray photoelectron spectroscopy confirmed that cyt C existed in the newly formed layer. Cyt C released from the cyt C-apatite composite layer for at least 10 days in the physiological salt solution.

Original languageEnglish
Pages (from-to)5742-5745
Number of pages4
JournalSurface and Coatings Technology
Issue number22-23
Publication statusPublished - 2008 Aug 30

Bibliographical note

Funding Information:
This work was supported by a grant (code #: 08K1501-01220) from Center for Nanostructured Materials Technology under 21st Century Frontier R&D Program of the Ministry of Science and Technology, Korea.

All Science Journal Classification (ASJC) codes

  • Chemistry(all)
  • Condensed Matter Physics
  • Surfaces and Interfaces
  • Surfaces, Coatings and Films
  • Materials Chemistry


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