Incorporation of cytochrome C with thin calcium phosphate film formed by electron-beam evaporation

Yan Li; In Seop Lee; Fu Zhai Cui; Zeng Lin; Jong Chul Park; Sung Min Chung

doi:10.1016/j.surfcoat.2008.06.082

Incorporation of cytochrome C with thin calcium phosphate film formed by electron-beam evaporation

Yan Li, In Seop Lee, Fu Zhai Cui, Zeng Lin, Jong Chul Park, Sung Min Chung

Department of Medical Engineering

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

Surface properties play a major role to determine the biocompatibility that is the ability of a material to perform with an appropriate host response in a specific application because biomaterials contact and interact with biological systems. Various methods have been studied to improve the surface properties and farther the osseous intergradation of bone implants. Cytochrome C (cyt C) was immobilized on the thin calcium phosphate films formed by electron-beam evaporation in the form of cyt C-apatite composite layer. The newly formed apatite layer was observed by scanning electron microscopy, and X-ray photoelectron spectroscopy confirmed that cyt C existed in the newly formed layer. Cyt C released from the cyt C-apatite composite layer for at least 10 days in the physiological salt solution.

Original language	English
Pages (from-to)	5742-5745
Number of pages	4
Journal	Surface and Coatings Technology
Volume	202
Issue number	22-23
DOIs	https://doi.org/10.1016/j.surfcoat.2008.06.082
Publication status	Published - 2008 Aug 30

Bibliographical note

Funding Information:
This work was supported by a grant (code #: 08K1501-01220) from Center for Nanostructured Materials Technology under 21st Century Frontier R&D Program of the Ministry of Science and Technology, Korea.

All Science Journal Classification (ASJC) codes

Chemistry(all)
Condensed Matter Physics
Surfaces and Interfaces
Surfaces, Coatings and Films
Materials Chemistry

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10.1016/j.surfcoat.2008.06.082

Cite this

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title = "Incorporation of cytochrome C with thin calcium phosphate film formed by electron-beam evaporation",

abstract = "Surface properties play a major role to determine the biocompatibility that is the ability of a material to perform with an appropriate host response in a specific application because biomaterials contact and interact with biological systems. Various methods have been studied to improve the surface properties and farther the osseous intergradation of bone implants. Cytochrome C (cyt C) was immobilized on the thin calcium phosphate films formed by electron-beam evaporation in the form of cyt C-apatite composite layer. The newly formed apatite layer was observed by scanning electron microscopy, and X-ray photoelectron spectroscopy confirmed that cyt C existed in the newly formed layer. Cyt C released from the cyt C-apatite composite layer for at least 10 days in the physiological salt solution.",

author = "Yan Li and Lee, {In Seop} and Cui, {Fu Zhai} and Zeng Lin and Park, {Jong Chul} and Chung, {Sung Min}",

note = "Funding Information: This work was supported by a grant (code #: 08K1501-01220) from Center for Nanostructured Materials Technology under 21st Century Frontier R&D Program of the Ministry of Science and Technology, Korea.",

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AU - Li, Yan

AU - Lee, In Seop

AU - Cui, Fu Zhai

AU - Lin, Zeng

AU - Park, Jong Chul

AU - Chung, Sung Min

N1 - Funding Information: This work was supported by a grant (code #: 08K1501-01220) from Center for Nanostructured Materials Technology under 21st Century Frontier R&D Program of the Ministry of Science and Technology, Korea.

PY - 2008/8/30

Y1 - 2008/8/30

N2 - Surface properties play a major role to determine the biocompatibility that is the ability of a material to perform with an appropriate host response in a specific application because biomaterials contact and interact with biological systems. Various methods have been studied to improve the surface properties and farther the osseous intergradation of bone implants. Cytochrome C (cyt C) was immobilized on the thin calcium phosphate films formed by electron-beam evaporation in the form of cyt C-apatite composite layer. The newly formed apatite layer was observed by scanning electron microscopy, and X-ray photoelectron spectroscopy confirmed that cyt C existed in the newly formed layer. Cyt C released from the cyt C-apatite composite layer for at least 10 days in the physiological salt solution.

AB - Surface properties play a major role to determine the biocompatibility that is the ability of a material to perform with an appropriate host response in a specific application because biomaterials contact and interact with biological systems. Various methods have been studied to improve the surface properties and farther the osseous intergradation of bone implants. Cytochrome C (cyt C) was immobilized on the thin calcium phosphate films formed by electron-beam evaporation in the form of cyt C-apatite composite layer. The newly formed apatite layer was observed by scanning electron microscopy, and X-ray photoelectron spectroscopy confirmed that cyt C existed in the newly formed layer. Cyt C released from the cyt C-apatite composite layer for at least 10 days in the physiological salt solution.

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Incorporation of cytochrome C with thin calcium phosphate film formed by electron-beam evaporation

Abstract

Bibliographical note

All Science Journal Classification (ASJC) codes

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