Incidence and risk factors of delayed postpolypectomy bleeding in patients with chronic liver disease

Hee Seung Lee, Jae Jun Park, Seung Up Kim, Jeung Eun Lee, Ga Lam Leem, Yonsoo Kim, Beom Kyung Kim, Jun Yong Park, Do Young Kim, Sang Hoon Ahn, Kwang Hyub Han

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13 Citations (Scopus)


Objective Hepatologists and colonoscopists often hesitate to perform a colonoscopic polypectomy in patients with chronic liver disease (CLD), especially those with cirrhosis, because of the risk of postpolypectomy bleeding (PPB). We aimed to investigate the incidence and risk factors of delayed PPB after a colonoscopic polypectomy in patients with CLD. Materials and methods In total, 152 patients with CLD who underwent colonoscopic polypectomy from December 2005 to December 2012 were retrospectively reviewed. Results Cirrhosis was identified in 80 (52.6%) patients. During the study period, 442 polyps were removed and delayed PPB developed in 14 (9.2%) patients. The incidence of delayed PPB was significantly higher in patients with cirrhosis than in those without the disease (13.8% [n = 11] vs. 4.2% [n = 3], p = 0.041). The polyp size (odds ratio, 1.087; 95% confidence interval, 1.009-1.172) and cirrhosis (odds ratio, 8.535; 95% confidence interval, 2.417-30.140) were independent risk factors for delayed PPB. In patients with cirrhosis, the optimal cut-off size to identify high-risk polyps for delayed PPB was 10 mm (area under the receiver operating characteristics curve, 0.737; sensitivity, 52%; specificity, 88%). Conclusion Caution is needed when colonoscopic polypectomy is planned in patients with CLD who have larger polyps and cirrhosis.

Original languageEnglish
Pages (from-to)618-624
Number of pages7
JournalScandinavian Journal of Gastroenterology
Issue number5
Publication statusPublished - 2016 May 3

Bibliographical note

Publisher Copyright:
© 2015 Taylor & Francis.

All Science Journal Classification (ASJC) codes

  • Gastroenterology


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