In vivo O2 measurement inside single photosynthetic cells

Seoung Jai Bai, Won Hyoung Ryu, Rainer J. Fasching, Arthur R. Grossman, Fritz B. Prinz

Research output: Contribution to journalArticlepeer-review

14 Citations (Scopus)


The oxygen evolution of single cells was investigated using a nano-probe with an ultra-micro electrode (UME) in a submicron sized system in combination with a micro-fluidic system. A single cell was immobilized in the micro-fluidic system and a nano-probe was inserted into the cytosolic space of the single cell. Then, the UME was used for an in vivo amperometric experiment at a fixed potential and electrochemical impedance spectroscopy to detect oxygen evolution of the single cell under various light intensities.

Original languageEnglish
Pages (from-to)1675-1681
Number of pages7
JournalBiotechnology Letters
Issue number8
Publication statusPublished - 2011 Aug

Bibliographical note

Funding Information:
Acknowledgment This work was supported by the Global Climate and Energy Project at Stanford University. S. Bai acknowledges additional support by Ministry of Environment under Environment Convergence Technology Project.

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Bioengineering
  • Applied Microbiology and Biotechnology


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