Improved enantioselectivity in asymmetric dihydroxylations of terminal olefins using pyrimidine ligands

Gerard A. Crispino; Kyu-Sung Jeong; Hartmuth C. Kolb; Zhi Min Wang; Daqiang Xu; K. Barry Sharpless

doi:10.1021/jo00067a002

Improved enantioselectivity in asymmetric dihydroxylations of terminal olefins using pyrimidine ligands

Gerard A. Crispino, Kyu-Sung Jeong, Hartmuth C. Kolb, Zhi Min Wang, Daqiang Xu, K. Barry Sharpless

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

245 Citations (Scopus)

Abstract

Bis-cinchona alkaloid substituted pyrimidine ligands were found to give improved enantioselectivity in the osmium-catalyzed asymmetric dihydroxylation (AD) of monosubstituted terminal olefins.

Original language	English
Pages (from-to)	3785-3786
Number of pages	2
Journal	Journal of Organic Chemistry
Volume	58
Issue number	3785
DOIs	https://doi.org/10.1021/jo00067a002
Publication status	Published - 1993 Jul

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@article{5cc90545ff314607a795366e6ed9b73c,

title = "Improved enantioselectivity in asymmetric dihydroxylations of terminal olefins using pyrimidine ligands",

abstract = "Bis-cinchona alkaloid substituted pyrimidine ligands were found to give improved enantioselectivity in the osmium-catalyzed asymmetric dihydroxylation (AD) of monosubstituted terminal olefins.",

author = "Crispino, {Gerard A.} and Kyu-Sung Jeong and Kolb, {Hartmuth C.} and Wang, {Zhi Min} and Daqiang Xu and Sharpless, {K. Barry}",

year = "1993",

month = jul,

doi = "10.1021/jo00067a002",

language = "English",

volume = "58",

pages = "3785--3786",

journal = "Journal of Organic Chemistry",

issn = "0022-3263",

publisher = "American Chemical Society",

number = "3785",

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TY - JOUR

T1 - Improved enantioselectivity in asymmetric dihydroxylations of terminal olefins using pyrimidine ligands

AU - Crispino, Gerard A.

AU - Jeong, Kyu-Sung

AU - Kolb, Hartmuth C.

AU - Wang, Zhi Min

AU - Xu, Daqiang

AU - Sharpless, K. Barry

PY - 1993/7

Y1 - 1993/7

N2 - Bis-cinchona alkaloid substituted pyrimidine ligands were found to give improved enantioselectivity in the osmium-catalyzed asymmetric dihydroxylation (AD) of monosubstituted terminal olefins.

AB - Bis-cinchona alkaloid substituted pyrimidine ligands were found to give improved enantioselectivity in the osmium-catalyzed asymmetric dihydroxylation (AD) of monosubstituted terminal olefins.

U2 - 10.1021/jo00067a002

DO - 10.1021/jo00067a002

M3 - Article

SN - 0022-3263

VL - 58

SP - 3785

EP - 3786

JO - Journal of Organic Chemistry

JF - Journal of Organic Chemistry

IS - 3785

ER -

Improved enantioselectivity in asymmetric dihydroxylations of terminal olefins using pyrimidine ligands

Abstract

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