Impact of high-normal blood pressure measured in emergency room on adverse cardiac events in acute myocardial infarction

Nam Sik Yoon, Myung Ho Jeong, Youngkeun Ahn, Jong Hyun Kim, Shung Chull Chae, Young Jo Kim, Seung Ho Hur, In Whan Seong, Taek Jong Hong, Donghoon Choi, Myeong Chan Cho, Chong Jin Kim, Ki Bae Seung, Wook Sung Chung, Yang Soo Jang, Jeong Gwan Cho, Seung Jung Park, Bon Kwon Koo, Byung Ok Kim, Chong Yun RhimDong Kyu Un, Doo Il Kim, Hyeon Cheol Gwon, In Ho Chae, Jae Young Rhew, Jang Ho Bae, Jei Keon Chae, Un Man Cho, Jin Yong Hwang, Jong Seon Park, Jung Han Yoon, Ju Young Yang, Kee Sik Kim, Keum Soo Park, Kyoo Rok Han, Kyoung Tae Jeong, Moo Hyun Kim, Myoung Yong Lee, Nae Hee Lee, Seok Kyu Oh, Seong Wook Park, Seong Woon Rha, Seung Jae Joo, Seung Jea Tahk, Soo Joong Kim, Tae Hoon Ahn, Young Youp Koh

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)


Background and Objectives: Prehypertension according to JNC7 is common and is associated with increased vascular mortality. The importance of management in high-normal blood pressure (BP) is underemphasized. Subjects and Methods: We analyzed major adverse cardiac events (MACEs) in the Korea Acute Myocardial Infarction Registry in normal BP (group I) and high-normal BP (group II) patients. Results: Among 14871 patients, 159 (61±12.3 years, 122 males) satisfied the study indication. Six-month and one-year clinical follow-up rate was 88.9% and 85.8%, respectively. Group I had 78 patients (60.9±12.4 years). Group II had 81 patients (61.6±12.5 years). Demographics of patients were not different between groups. Treatment strategy was not different. Initial Thrombolysis in Myocardial Infarction flow grade 0 was less frequent in group II (n=32, 47.1%) than in group I (n=16, 21.9%) (p=0.001). Successful intervention rate was not different between group II (93.8%) and group I (97.1%) (p=0.590). Six-month MACE occurred in 3 patients in group I (4.4%) and 10 in group II (15.6%) (p=0.031). Compared with normal BP, the odds ratio for patients with high-normal BP was 1.147 (p=0.045, 95% confidence interval 1.011-1.402) for 6-month MACE. Conclusion: Even though high-normal BP patients had a better baseline clinical status, the prognosis was poorer than patients with normal BP. Therapeutic BP target goal for the patients with acute myocardial infarction should be < 140/90 mm Hg, which is recommended in JNC7.

Original languageEnglish
Pages (from-to)304-310
Number of pages7
JournalKorean Circulation Journal
Issue number5
Publication statusPublished - 2012 May

All Science Journal Classification (ASJC) codes

  • Internal Medicine
  • Cardiology and Cardiovascular Medicine


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