Impact of diabetes mellitus on angiographic and clinical outcomes in the drug-eluting stents era

Tae Hyun Yang, Seong Wook Park, Myeong Ki Hong, Duk Woo Park, Kyoung Min Park, Young Hak Kim, Ki Hoon Han, Whan Lee Cheol, Sang Sig Cheong, Jae Joong Kim, Seung Jung Park

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41 Citations (Scopus)


The effect of diabetes mellitus (DM) on angiographic restenosis and clinical outcomes after implantation of drug-eluting stents (DESs) has not been investigated in real-world practice. This study consisted of 226 patients who had DM and 560 patients who did not who underwent DES implantation between February 2003 and December 2003. We retrospectively compared the incidence of 6-month angiographic restenosis and 9-month major adverse cardiac events (MACEs), defined as cardiac death, myocardial infarction, and target lesion revascularization, between patients with and without DM. The 6-month angiographic restenotic rate (10.1% vs 8.2%, p = 0.41) and late loss (0.41 ± 0.63 vs 0.36 ± 0.65, p = 0.31) were similar between patients with and without DM. In addition, incidences of MACEs (4.9% vs 4.8%, p = 1.00) and target lesion revascularization (4.4% vs 4.1%, p = 0.84) were similar. Patients who had insulin-dependent DM manifested higher prevalences of restenosis (25.0% vs 8.5%, p = 0.04) and MACEs (17.2% vs 3.1%, p = 0.01) compared with patients who had non-insulin-dependent DM. In conclusion, in this study of real-world patients who underwent DES implantation, patients who had DM had restenotic rates and clinical outcomes that were similar to those in patients who did not have DM.

Original languageEnglish
Pages (from-to)1389-1392
Number of pages4
JournalAmerican Journal of Cardiology
Issue number10
Publication statusPublished - 2005 Nov 15

Bibliographical note

Funding Information:
This study was supported in part by the Cardiovascular Research Foundation, Seoul, Korea, and by Grant 0412-CR02-0704-0001 from the Korea Health 21 R&D Project, Ministry of Health & Welfare, Seoul, Korea.

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine


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