Abstract
BACKGROUND AND PURPOSE: Mechanical thrombectomy with proximal flow control and forced aspiration may improve the outcome of endovascular revascularization therapy for patients with acute stroke. The purpose of this study was to compare the impact of balloon-guiding catheter locations in patients treated for anterior circulation acute ischemic stroke using mechanical thrombectomy. MATERIALS AND METHODS: The influence of the balloon-guiding catheter location (proximal, balloon-guiding catheter tip proximal to C1 vertebral body; distal, between the skull base and the C1 vertebral body) was analyzed in patients with acute anterior circulation stroke treated with stent-retriever thrombectomy. The baseline angiographic/clinical characteristics, time intervals, recanalization rates, and clinical outcomes were compared. RESULTS: The clinical analysis included 102 patients (mean age, 69.5±12.8 years; male/female ratio=52:50). The balloon-guiding catheter was located distally in 49 patients and proximally in 53 patients for flow control and forced aspiration during stent retrieval. The puncture-to-recanalization time was shorter in the distal group than in the proximal group (40 versus 56 minutes, P=.02). Successful and complete recanalizations were more frequently achieved in the distal group compared with the proximal group (98.0% versus 75.5%. P = .003; 67.3% versus 45.3%, P = .04, respectively). Multivariate analysis showed that the distal catheterization location was independently associated with successful recanalization (adjusted OR, 13.4; 95% CI, 2.4 -254.8; P = .02). CONCLUSIONS: Location of the balloon-guiding catheter has a significant impact on recanalization in patients with acute stroke. The balloon-guiding catheter should be positioned as distally as safely possible in the cervical ICA for maximally effective thrombectomy.
| Original language | English |
|---|---|
| Pages (from-to) | 840-844 |
| Number of pages | 5 |
| Journal | American Journal of Neuroradiology |
| Volume | 40 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - 2019 |
Bibliographical note
Funding Information:From the Department of Radiology (D.E.J., J.W.K., B.M.K., D.J.K.), Yonsei University College of Medicine, Severance Hospital, Seoul, South Korea; Department of Neurology (D.E.J.), YeongNam University College of Medicine, Daegu, South Korea; and Department of Mechanical and Aerospace Engineering (W.H.), Seoul National University, Seoul, South Korea. This study was supported by a grant from the Research Institute of Radiological Science, Yonsei University College of Medicine (grant No. 4-2017-0877). Please address correspondence to Dong Joon Kim, MD, PhD, Department of Radiology, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 03722, South Korea; e-mail: djkimmd@yuhs.ac
Publisher Copyright:
© 2019 American Society of Neuroradiology. All rights reserved.
All Science Journal Classification (ASJC) codes
- Radiology Nuclear Medicine and imaging
- Clinical Neurology