Idiopathic solitary neuroma of skin with unusual histologic changes

Sung Ku Ahn, Eung Ho Choi, Jin Hyoung Won, Seung Hun Lee

Research output: Contribution to journalArticlepeer-review


We report herein a case of idiopathic solitary neuroma with vascular proliferation and neurofibroma‐like features. Clinically, the skin lesion was a 0.7 cm nodule without tenderness on die forearm. Histologically, there was vascular proliferation in the upper dermis, some neural structures among the proliferative vasculature in the mid dermis and large bundles of neural structures extending in various directions in the mid and deep dermis (resembling neurofibroma). Special stains, such as Masson's trichrome and Luxol fast blue, and immunohistochemical studies, including S‐100 protein, neuron‐specific enolase (NSE), vimentin, desmin, factor‐VIII related antigen and epithelial membrane antigen (EMA), were added for this very rare case.

Original languageEnglish
Pages (from-to)570-573
Number of pages4
JournalJournal of Cutaneous Pathology
Issue number6
Publication statusPublished - 1995 Dec

All Science Journal Classification (ASJC) codes

  • Pathology and Forensic Medicine
  • Histology
  • Dermatology


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