TY - JOUR
T1 - Idiopathic solitary neuroma of skin with unusual histologic changes
AU - Ahn, Sung Ku
AU - Choi, Eung Ho
AU - Won, Jin Hyoung
AU - Lee, Seung Hun
PY - 1995/12
Y1 - 1995/12
N2 - We report herein a case of idiopathic solitary neuroma with vascular proliferation and neurofibroma‐like features. Clinically, the skin lesion was a 0.7 cm nodule without tenderness on die forearm. Histologically, there was vascular proliferation in the upper dermis, some neural structures among the proliferative vasculature in the mid dermis and large bundles of neural structures extending in various directions in the mid and deep dermis (resembling neurofibroma). Special stains, such as Masson's trichrome and Luxol fast blue, and immunohistochemical studies, including S‐100 protein, neuron‐specific enolase (NSE), vimentin, desmin, factor‐VIII related antigen and epithelial membrane antigen (EMA), were added for this very rare case.
AB - We report herein a case of idiopathic solitary neuroma with vascular proliferation and neurofibroma‐like features. Clinically, the skin lesion was a 0.7 cm nodule without tenderness on die forearm. Histologically, there was vascular proliferation in the upper dermis, some neural structures among the proliferative vasculature in the mid dermis and large bundles of neural structures extending in various directions in the mid and deep dermis (resembling neurofibroma). Special stains, such as Masson's trichrome and Luxol fast blue, and immunohistochemical studies, including S‐100 protein, neuron‐specific enolase (NSE), vimentin, desmin, factor‐VIII related antigen and epithelial membrane antigen (EMA), were added for this very rare case.
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U2 - 10.1111/j.1600-0560.1995.tb01153.x
DO - 10.1111/j.1600-0560.1995.tb01153.x
M3 - Article
C2 - 8835177
AN - SCOPUS:0029557992
SN - 0303-6987
VL - 22
SP - 570
EP - 573
JO - Journal of Cutaneous Pathology
JF - Journal of Cutaneous Pathology
IS - 6
ER -