Hydroacylation of 1-alkene with heteroaromatic aldehyde by Rh(I) and additives

Chul Ho Jun; Dae Yon Lee; Jun Bae Hong

doi:10.1016/S0040-4039(97)01562-1

Hydroacylation of 1-alkene with heteroaromatic aldehyde by Rh(I) and additives

Chul Ho Jun, Dae Yon Lee, Jun Bae Hong

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

72 Citations (Scopus)

Abstract

Hydroacylation of 1-alkene with a heteroaromatic aldehyde such as pyridinecarboxaldehyde, thiophenecarboxaldehyde and furfural derivatives under cocatalyst of Wilkinson's complex and 2-amino-3-picoline gave poor yield of hydroacylated product. The addition of a catalytic amount of bis(cyclopentadienyl)zirconium dichloride or bis(cyclopentadienyl)titanium dichloride as an additive dramatically increased the yield of the hydroacylated ketone product.

Original language	English
Pages (from-to)	6673-6676
Number of pages	4
Journal	Tetrahedron Letters
Volume	38
Issue number	38
DOIs	https://doi.org/10.1016/S0040-4039(97)01562-1
Publication status	Published - 1997 Sept 22

Bibliographical note

Funding Information:
This study was supported in part by the Basic Science Research Institute Program, Ministry of Education (Project No. BSRI-96-3422) and the Korea Science and Engineering Foundation (Grant 961-0306-054-2).

All Science Journal Classification (ASJC) codes

Biochemistry
Drug Discovery
Organic Chemistry

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title = "Hydroacylation of 1-alkene with heteroaromatic aldehyde by Rh(I) and additives",

abstract = "Hydroacylation of 1-alkene with a heteroaromatic aldehyde such as pyridinecarboxaldehyde, thiophenecarboxaldehyde and furfural derivatives under cocatalyst of Wilkinson's complex and 2-amino-3-picoline gave poor yield of hydroacylated product. The addition of a catalytic amount of bis(cyclopentadienyl)zirconium dichloride or bis(cyclopentadienyl)titanium dichloride as an additive dramatically increased the yield of the hydroacylated ketone product.",

author = "Jun, {Chul Ho} and Lee, {Dae Yon} and Hong, {Jun Bae}",

note = "Funding Information: This study was supported in part by the Basic Science Research Institute Program, Ministry of Education (Project No. BSRI-96-3422) and the Korea Science and Engineering Foundation (Grant 961-0306-054-2).",

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doi = "10.1016/S0040-4039(97)01562-1",

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T1 - Hydroacylation of 1-alkene with heteroaromatic aldehyde by Rh(I) and additives

AU - Jun, Chul Ho

AU - Lee, Dae Yon

AU - Hong, Jun Bae

N1 - Funding Information: This study was supported in part by the Basic Science Research Institute Program, Ministry of Education (Project No. BSRI-96-3422) and the Korea Science and Engineering Foundation (Grant 961-0306-054-2).

PY - 1997/9/22

Y1 - 1997/9/22

N2 - Hydroacylation of 1-alkene with a heteroaromatic aldehyde such as pyridinecarboxaldehyde, thiophenecarboxaldehyde and furfural derivatives under cocatalyst of Wilkinson's complex and 2-amino-3-picoline gave poor yield of hydroacylated product. The addition of a catalytic amount of bis(cyclopentadienyl)zirconium dichloride or bis(cyclopentadienyl)titanium dichloride as an additive dramatically increased the yield of the hydroacylated ketone product.

AB - Hydroacylation of 1-alkene with a heteroaromatic aldehyde such as pyridinecarboxaldehyde, thiophenecarboxaldehyde and furfural derivatives under cocatalyst of Wilkinson's complex and 2-amino-3-picoline gave poor yield of hydroacylated product. The addition of a catalytic amount of bis(cyclopentadienyl)zirconium dichloride or bis(cyclopentadienyl)titanium dichloride as an additive dramatically increased the yield of the hydroacylated ketone product.

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ER -

Hydroacylation of 1-alkene with heteroaromatic aldehyde by Rh(I) and additives

Abstract

Bibliographical note

All Science Journal Classification (ASJC) codes

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