Human Monkeypox: A Comprehensive Narrative Review and Analysis of the Public Health Implications

Francesco Di Gennaro; Nicola Veronese; Claudia Marotta; Jae Il Shin; Ai Koyanagi; Andrea Silenzi; Mario Antunes; Annalisa Saracino; Davide Fiore Bavaro; Pinar Soysal; Francesco Vladimiro Segala; Laurie Butler; Eugenio Milano; Mario Barbagallo; Yvonne Barnett; Christopher Parris; Emanuele Nicastri; Damiano Pizzol; Lee Smith

doi:10.3390/microorganisms10081633

Human Monkeypox: A Comprehensive Narrative Review and Analysis of the Public Health Implications

Francesco Di Gennaro, Nicola Veronese, Claudia Marotta, Jae Il Shin, Ai Koyanagi, Andrea Silenzi, Mario Antunes, Annalisa Saracino, Davide Fiore Bavaro, Pinar Soysal, Francesco Vladimiro Segala, Laurie Butler, Eugenio Milano, Mario Barbagallo, Yvonne Barnett, Christopher Parris, Emanuele Nicastri, Damiano Pizzol, Lee Smith

Department of Pediatrics

Research output: Contribution to journal › Review article › peer-review

52 Citations (Scopus)

Abstract

Recently, numerous cases of monkeypox were reported from several non-endemic countries in Europe, North America, and Oceania, suggesting an unusual and alarming public health issue, particularly considering that the disease is not directly related to human or animal travels. Attention is currently being drawn to this phenomenon since more than 70% of the global population is no longer vaccinated against smallpox. Indeed, the smallpox vaccination also confers some indirect degree of protection against other poxviruses, including monkeypox. We performed a narrative review to describe the existing literature with regard to monkeypox using the MEDLINE, EMBASE, and Scopus databases. This review aims to provide updated evidence of findings on the epidemiology, clinical features, diagnosis, management, and prevention of monkeypox, also considering the concurrent zoonotic pandemic caused by the COVID-19 coronavirus, SARS-CoV-2.

Original language	English
Article number	1633
Journal	Microorganisms
Volume	10
Issue number	8
DOIs	https://doi.org/10.3390/microorganisms10081633
Publication status	Published - 2022 Aug

Bibliographical note

Publisher Copyright:
© 2022 by the authors.

All Science Journal Classification (ASJC) codes

Microbiology
Microbiology (medical)
Virology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.3390/microorganisms10081633

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Di Gennaro, F., Veronese, N., Marotta, C., Shin, J. I., Koyanagi, A., Silenzi, A., Antunes, M., Saracino, A., Bavaro, D. F., Soysal, P., Segala, F. V., Butler, L., Milano, E., Barbagallo, M., Barnett, Y., Parris, C., Nicastri, E., Pizzol, D., & Smith, L. (2022). Human Monkeypox: A Comprehensive Narrative Review and Analysis of the Public Health Implications. Microorganisms, 10(8), Article 1633. https://doi.org/10.3390/microorganisms10081633

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abstract = "Recently, numerous cases of monkeypox were reported from several non-endemic countries in Europe, North America, and Oceania, suggesting an unusual and alarming public health issue, particularly considering that the disease is not directly related to human or animal travels. Attention is currently being drawn to this phenomenon since more than 70% of the global population is no longer vaccinated against smallpox. Indeed, the smallpox vaccination also confers some indirect degree of protection against other poxviruses, including monkeypox. We performed a narrative review to describe the existing literature with regard to monkeypox using the MEDLINE, EMBASE, and Scopus databases. This review aims to provide updated evidence of findings on the epidemiology, clinical features, diagnosis, management, and prevention of monkeypox, also considering the concurrent zoonotic pandemic caused by the COVID-19 coronavirus, SARS-CoV-2.",

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author = "{Di Gennaro}, Francesco and Nicola Veronese and Claudia Marotta and Shin, {Jae Il} and Ai Koyanagi and Andrea Silenzi and Mario Antunes and Annalisa Saracino and Bavaro, {Davide Fiore} and Pinar Soysal and Segala, {Francesco Vladimiro} and Laurie Butler and Eugenio Milano and Mario Barbagallo and Yvonne Barnett and Christopher Parris and Emanuele Nicastri and Damiano Pizzol and Lee Smith",

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doi = "10.3390/microorganisms10081633",

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Di Gennaro, F, Veronese, N, Marotta, C, Shin, JI, Koyanagi, A, Silenzi, A, Antunes, M, Saracino, A, Bavaro, DF, Soysal, P, Segala, FV, Butler, L, Milano, E, Barbagallo, M, Barnett, Y, Parris, C, Nicastri, E, Pizzol, D & Smith, L 2022, 'Human Monkeypox: A Comprehensive Narrative Review and Analysis of the Public Health Implications', Microorganisms, vol. 10, no. 8, 1633. https://doi.org/10.3390/microorganisms10081633

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AU - Di Gennaro, Francesco

AU - Veronese, Nicola

AU - Marotta, Claudia

AU - Shin, Jae Il

AU - Koyanagi, Ai

AU - Silenzi, Andrea

AU - Antunes, Mario

AU - Saracino, Annalisa

AU - Bavaro, Davide Fiore

AU - Soysal, Pinar

AU - Segala, Francesco Vladimiro

AU - Butler, Laurie

AU - Milano, Eugenio

AU - Barbagallo, Mario

AU - Barnett, Yvonne

AU - Parris, Christopher

AU - Nicastri, Emanuele

AU - Pizzol, Damiano

AU - Smith, Lee

PY - 2022/8

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AB - Recently, numerous cases of monkeypox were reported from several non-endemic countries in Europe, North America, and Oceania, suggesting an unusual and alarming public health issue, particularly considering that the disease is not directly related to human or animal travels. Attention is currently being drawn to this phenomenon since more than 70% of the global population is no longer vaccinated against smallpox. Indeed, the smallpox vaccination also confers some indirect degree of protection against other poxviruses, including monkeypox. We performed a narrative review to describe the existing literature with regard to monkeypox using the MEDLINE, EMBASE, and Scopus databases. This review aims to provide updated evidence of findings on the epidemiology, clinical features, diagnosis, management, and prevention of monkeypox, also considering the concurrent zoonotic pandemic caused by the COVID-19 coronavirus, SARS-CoV-2.

KW - epidemiology

KW - monkeypox (MPX)

KW - smallpox

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Human Monkeypox: A Comprehensive Narrative Review and Analysis of the Public Health Implications

Abstract

Bibliographical note

All Science Journal Classification (ASJC) codes

UN SDGs

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