TY - JOUR
T1 - Hemorrhagic transformation of ischemic stroke
T2 - Severe complications of prosthetic valve endocarditis
AU - Kim, Jin Sun
AU - Yang, Woo In
AU - Shim, Chi Young
AU - Ha, Jong Won
AU - Chung, Namsik
AU - Chang, Hyuk Jae
PY - 2011/8
Y1 - 2011/8
N2 - Ischemic stroke is a common complication of infective endocarditis (IE), occurring in 20-40% of left side IE cases. In these subsets, anticoagulation therapy may provoke hemorrhagic transformation (HT) of ischemic stroke, and complications of this magnitude deteriorate the clinical course for IE patients. However, in cases of IE complicated with a mechanical prosthetic valve, the physician can be concerned over the maintenance of anticoagulation due to the risk of thrombotic complication. According to our retrospective review, HT of ischemic stroke in prosthetic valve endocarditis occurred 13.8% (4/29) of the time in a variety of situations. Some of these even arose in patients with a subtherapeutic range of prothrombin time.
AB - Ischemic stroke is a common complication of infective endocarditis (IE), occurring in 20-40% of left side IE cases. In these subsets, anticoagulation therapy may provoke hemorrhagic transformation (HT) of ischemic stroke, and complications of this magnitude deteriorate the clinical course for IE patients. However, in cases of IE complicated with a mechanical prosthetic valve, the physician can be concerned over the maintenance of anticoagulation due to the risk of thrombotic complication. According to our retrospective review, HT of ischemic stroke in prosthetic valve endocarditis occurred 13.8% (4/29) of the time in a variety of situations. Some of these even arose in patients with a subtherapeutic range of prothrombin time.
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U2 - 10.4070/kcj.2011.41.8.490
DO - 10.4070/kcj.2011.41.8.490
M3 - Article
C2 - 21949537
AN - SCOPUS:80052924687
SN - 1738-5520
VL - 41
SP - 490
EP - 493
JO - Korean Circulation Journal
JF - Korean Circulation Journal
IS - 8
ER -