Heavy metal analysis of ortho MTA and ProRoot MTA

Seok Woo Chang; Seung Ho Baek; Hyeong Cheol Yang; Deog Gyu Seo; Sung Tae Hong; Seung Hyun Han; Yoon Lee; Yu Gu; Ho Bum Kwon; Woocheol Lee; Kwang Shik Bae; Kee Yeon Kum

doi:10.1016/j.joen.2011.08.020

Heavy metal analysis of ortho MTA and ProRoot MTA

Seok Woo Chang, Seung Ho Baek, Hyeong Cheol Yang, Deog Gyu Seo, Sung Tae Hong, Seung Hyun Han, Yoon Lee, Yu Gu, Ho Bum Kwon, Woocheol Lee, Kwang Shik Bae, Kee Yeon Kum

Dentistry

Research output: Contribution to journal › Article › peer-review

53 Citations (Scopus)

Abstract

Introduction: Recently, several kinds of mineral trioxide aggregate (MTA)-based products have been introduced in endodontics. Ortho MTA (BioMTA, Seoul, Republic of Korea) is one of those products, which was developed for retrograde filling, perforation repair, orthograde root canal obturation, and direct pulp capping. The inclusion of heavy metals in MTA-based materials is of concern because they come into direct contact with hard and soft tissues. The aim of this study was to investigate and compare the levels of arsenic (As), chromium (Cr), hexavalent chromium (Cr ⁶⁺), and lead (Pb) in Ortho MTA and ProRoot MTA. Methods: One gram of each MTA was digested using a mixture of hydrochloric and nitric acids and filtered. The As, Cr, and Pb in the resulting filtrates were analyzed by inductively coupled plasma-optical emission spectrometry. The level of Cr ⁶⁺ was measured by the methods suggested in the Korean Standard L 5221. The results were statistically analyzed using the Mann-Whitney U test. Results: The concentration of As in ProRoot MTA was 1.16 ppm, but As was not detected in Ortho MTA. Cr ⁶⁺ and Pb were not detected in either MTA. Ortho MTA contained significantly less Cr than ProRoot MTA (P <.05). Conclusions: Ortho MTA and ProRoot MTA meet the ISO specification 9917-1 regarding the safety limits of As and Pb and are safe biomaterials when the purity of As, Cr ⁶⁺, and Pb is considered.

Original language	English
Pages (from-to)	1673-1676
Number of pages	4
Journal	Journal of endodontics
Volume	37
Issue number	12
DOIs	https://doi.org/10.1016/j.joen.2011.08.020
Publication status	Published - 2011 Dec

Bibliographical note

Funding Information:
This research was supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education, Science and Technology (MEST) (2011-0014231). This study was supported by NRF of Korea funded by the MEST (2009-0086835, 2010-0029116). This study was also supported by Samsung Biomedical Research Institute grant (SBRI C-B1-310-1) and Samsung Medical Center Clinical Research Development Program grant (CRS-111-14-1).

All Science Journal Classification (ASJC) codes

Dentistry(all)

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10.1016/j.joen.2011.08.020

Cite this

@article{937d9dd1d7704e81a66034b6bad91307,

title = "Heavy metal analysis of ortho MTA and ProRoot MTA",

abstract = "Introduction: Recently, several kinds of mineral trioxide aggregate (MTA)-based products have been introduced in endodontics. Ortho MTA (BioMTA, Seoul, Republic of Korea) is one of those products, which was developed for retrograde filling, perforation repair, orthograde root canal obturation, and direct pulp capping. The inclusion of heavy metals in MTA-based materials is of concern because they come into direct contact with hard and soft tissues. The aim of this study was to investigate and compare the levels of arsenic (As), chromium (Cr), hexavalent chromium (Cr 6+), and lead (Pb) in Ortho MTA and ProRoot MTA. Methods: One gram of each MTA was digested using a mixture of hydrochloric and nitric acids and filtered. The As, Cr, and Pb in the resulting filtrates were analyzed by inductively coupled plasma-optical emission spectrometry. The level of Cr 6+ was measured by the methods suggested in the Korean Standard L 5221. The results were statistically analyzed using the Mann-Whitney U test. Results: The concentration of As in ProRoot MTA was 1.16 ppm, but As was not detected in Ortho MTA. Cr 6+ and Pb were not detected in either MTA. Ortho MTA contained significantly less Cr than ProRoot MTA (P <.05). Conclusions: Ortho MTA and ProRoot MTA meet the ISO specification 9917-1 regarding the safety limits of As and Pb and are safe biomaterials when the purity of As, Cr 6+, and Pb is considered.",

author = "Chang, {Seok Woo} and Baek, {Seung Ho} and Yang, {Hyeong Cheol} and Seo, {Deog Gyu} and Hong, {Sung Tae} and Han, {Seung Hyun} and Yoon Lee and Yu Gu and Kwon, {Ho Bum} and Woocheol Lee and Bae, {Kwang Shik} and Kum, {Kee Yeon}",

note = "Funding Information: This research was supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education, Science and Technology (MEST) (2011-0014231). This study was supported by NRF of Korea funded by the MEST (2009-0086835, 2010-0029116). This study was also supported by Samsung Biomedical Research Institute grant (SBRI C-B1-310-1) and Samsung Medical Center Clinical Research Development Program grant (CRS-111-14-1). ",

year = "2011",

month = dec,

doi = "10.1016/j.joen.2011.08.020",

language = "English",

volume = "37",

pages = "1673--1676",

journal = "Journal of Endodontics",

issn = "0099-2399",

publisher = "Elsevier Inc.",

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T1 - Heavy metal analysis of ortho MTA and ProRoot MTA

AU - Chang, Seok Woo

AU - Baek, Seung Ho

AU - Yang, Hyeong Cheol

AU - Seo, Deog Gyu

AU - Hong, Sung Tae

AU - Han, Seung Hyun

AU - Lee, Yoon

AU - Gu, Yu

AU - Kwon, Ho Bum

AU - Lee, Woocheol

AU - Bae, Kwang Shik

AU - Kum, Kee Yeon

N1 - Funding Information: This research was supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education, Science and Technology (MEST) (2011-0014231). This study was supported by NRF of Korea funded by the MEST (2009-0086835, 2010-0029116). This study was also supported by Samsung Biomedical Research Institute grant (SBRI C-B1-310-1) and Samsung Medical Center Clinical Research Development Program grant (CRS-111-14-1).

PY - 2011/12

Y1 - 2011/12

N2 - Introduction: Recently, several kinds of mineral trioxide aggregate (MTA)-based products have been introduced in endodontics. Ortho MTA (BioMTA, Seoul, Republic of Korea) is one of those products, which was developed for retrograde filling, perforation repair, orthograde root canal obturation, and direct pulp capping. The inclusion of heavy metals in MTA-based materials is of concern because they come into direct contact with hard and soft tissues. The aim of this study was to investigate and compare the levels of arsenic (As), chromium (Cr), hexavalent chromium (Cr 6+), and lead (Pb) in Ortho MTA and ProRoot MTA. Methods: One gram of each MTA was digested using a mixture of hydrochloric and nitric acids and filtered. The As, Cr, and Pb in the resulting filtrates were analyzed by inductively coupled plasma-optical emission spectrometry. The level of Cr 6+ was measured by the methods suggested in the Korean Standard L 5221. The results were statistically analyzed using the Mann-Whitney U test. Results: The concentration of As in ProRoot MTA was 1.16 ppm, but As was not detected in Ortho MTA. Cr 6+ and Pb were not detected in either MTA. Ortho MTA contained significantly less Cr than ProRoot MTA (P <.05). Conclusions: Ortho MTA and ProRoot MTA meet the ISO specification 9917-1 regarding the safety limits of As and Pb and are safe biomaterials when the purity of As, Cr 6+, and Pb is considered.

AB - Introduction: Recently, several kinds of mineral trioxide aggregate (MTA)-based products have been introduced in endodontics. Ortho MTA (BioMTA, Seoul, Republic of Korea) is one of those products, which was developed for retrograde filling, perforation repair, orthograde root canal obturation, and direct pulp capping. The inclusion of heavy metals in MTA-based materials is of concern because they come into direct contact with hard and soft tissues. The aim of this study was to investigate and compare the levels of arsenic (As), chromium (Cr), hexavalent chromium (Cr 6+), and lead (Pb) in Ortho MTA and ProRoot MTA. Methods: One gram of each MTA was digested using a mixture of hydrochloric and nitric acids and filtered. The As, Cr, and Pb in the resulting filtrates were analyzed by inductively coupled plasma-optical emission spectrometry. The level of Cr 6+ was measured by the methods suggested in the Korean Standard L 5221. The results were statistically analyzed using the Mann-Whitney U test. Results: The concentration of As in ProRoot MTA was 1.16 ppm, but As was not detected in Ortho MTA. Cr 6+ and Pb were not detected in either MTA. Ortho MTA contained significantly less Cr than ProRoot MTA (P <.05). Conclusions: Ortho MTA and ProRoot MTA meet the ISO specification 9917-1 regarding the safety limits of As and Pb and are safe biomaterials when the purity of As, Cr 6+, and Pb is considered.

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Heavy metal analysis of ortho MTA and ProRoot MTA

Abstract

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