Heat shock protein 90 inhibitor decreases collagen synthesis of keloid fibroblasts and attenuates the extracellular matrix on the keloid spheroid model

Medicine and Dentistry

• Keloid 100%
• Tanespimycin 80%
• Heat Shock Protein 90 50%
• Transforming Growth Factor 50%
• Tumor Spheroid 40%
• Collagen Type 1 30%
• Fibroblast 30%
• Messenger RNA 20%
• Collagen 20%
• Fibrinogen 20%
• Hsp90 Inhibitor 20%
• Trichrome 20%
• Collagen Type 3 20%
• Western Blot 20%
• Quantitative Reverse Transcription Polymerase Chain Reaction 20%
• Tissues 20%
• Pathogenesis 10%
• Therapy Effect 10%
• Protein 10%
• Extracellular Matrix 10%
• Enzyme Linked Immunosorbent Assay 10%
• Protein Expression 10%
• Immunohistochemistry 10%
• Fibronectin 10%
• Chaperone 10%
• Elastin 10%
• Scleroprotein 10%
• Collagen Synthesis 10%
• Analysis 10%
• Therapeutic Procedure 10%
• Growth Factor Receptor 10%

Biochemistry, Genetics and Molecular Biology

• Heat Shock Protein 50%
• Transforming Growth Factor 50%
• Tumor Spheroid 40%
• Fibroblast 30%
• Type I Collagen 30%
• Staining 20%
• Heat Shock Protein 90 Inhibitor 20%
• Messenger RNA 20%
• Collagen 20%
• Degradation 10%
• Protein Expression 10%
• Lysozyme 10%
• Collagen Synthesis 10%
• Extracellular Matrix Proteins 10%
• Fibronectin 10%
• Growth Factor Receptor 10%
• Elastin 10%
• Protein 10%