TY - JOUR
T1 - Health-Related Quality of Life of Kidney Transplantation Patients
T2 - Results from the Korean Cohort Study for Outcome in Patients with Kidney Transplantation (KNOW-KT) Study
AU - KNOW-KT Study Group
AU - Lim, H. J.
AU - Koo, T. Y.
AU - Lee, J.
AU - Huh, K. H.
AU - Park, J. B.
AU - Cho, J.
AU - Lee, S.
AU - Ro, H.
AU - Han, S.
AU - Park, B.
AU - Park, S.
AU - Chung, W.
AU - Park, S. K.
AU - Kim, C.
AU - Kim, S. J.
AU - Kim, Y. S.
AU - Ahn, C.
AU - Yang, J.
N1 - Funding Information:
Research supported by funds ( 2013E3301601 ) from Korea Centers for Disease Control & Prevention .
Publisher Copyright:
© 2016 Elsevier Inc.
PY - 2016/4/1
Y1 - 2016/4/1
N2 - Background As patient and graft survival rates have been improving after kidney transplantation, health-related quality of life (HR-QOL) has become an important indicator of effective treatment. This study aimed to evaluate changes in HR-QOL after kidney transplantation. Materials and Methods The KoreaN cohort study for Outcome in patients With Kidney Transplantation (KNOW-KT) is a multicenter, observational, 9-year, cohort study. The HR-QOL of patients in the KNOW-KT study was assessed before transplantation and 2 years after transplantation using the Kidney Disease Quality of Life Short Form (KDQOL-SF) including chronic kidney disease targeted area and the Medical Outcome Study 36-item Short Form Health Survey (SF-36). Multivariate linear regression was used to identify significant factors associated with follow-up QOL scores. Results A total of 175 patients from 8 centers were analyzed. All QOL scores including the total QOL score, chronic kidney disease targeted score, and SF-36 at the 2-year follow-up were significantly increased compared to baseline values. Both physical and mental scale scores were improved after transplantation. Conclusion The QOL scores for both the mental and physical scales were improved at 2 years after kidney transplantation. High glomerular filtration rate at 2 years, high baseline QOL score, and low body mass index were associated with good follow-up QOL scores. Kidney transplantation for an Asian population with end-stage renal disease can result in better QOL as well as better patient and graft survival.
AB - Background As patient and graft survival rates have been improving after kidney transplantation, health-related quality of life (HR-QOL) has become an important indicator of effective treatment. This study aimed to evaluate changes in HR-QOL after kidney transplantation. Materials and Methods The KoreaN cohort study for Outcome in patients With Kidney Transplantation (KNOW-KT) is a multicenter, observational, 9-year, cohort study. The HR-QOL of patients in the KNOW-KT study was assessed before transplantation and 2 years after transplantation using the Kidney Disease Quality of Life Short Form (KDQOL-SF) including chronic kidney disease targeted area and the Medical Outcome Study 36-item Short Form Health Survey (SF-36). Multivariate linear regression was used to identify significant factors associated with follow-up QOL scores. Results A total of 175 patients from 8 centers were analyzed. All QOL scores including the total QOL score, chronic kidney disease targeted score, and SF-36 at the 2-year follow-up were significantly increased compared to baseline values. Both physical and mental scale scores were improved after transplantation. Conclusion The QOL scores for both the mental and physical scales were improved at 2 years after kidney transplantation. High glomerular filtration rate at 2 years, high baseline QOL score, and low body mass index were associated with good follow-up QOL scores. Kidney transplantation for an Asian population with end-stage renal disease can result in better QOL as well as better patient and graft survival.
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U2 - 10.1016/j.transproceed.2015.12.101
DO - 10.1016/j.transproceed.2015.12.101
M3 - Article
C2 - 27234749
AN - SCOPUS:84969949506
SN - 0041-1345
VL - 48
SP - 844
EP - 847
JO - Transplantation Proceedings
JF - Transplantation Proceedings
IS - 3
ER -