Gender-specific differences of interaction between obesity and air pollution on stroke and cardiovascular diseases in Chinese adults from a high pollution range area: A large population based cross sectional study

Xiao Di Qin; Zhengmin Qian; Michael G. Vaughn; Edwin Trevathan; Brett Emo; Gunther Paul; Wan Hui Ren; Yuan Tao Hao; Guang Hui Dong

doi:10.1016/j.scitotenv.2015.05.041

Gender-specific differences of interaction between obesity and air pollution on stroke and cardiovascular diseases in Chinese adults from a high pollution range area: A large population based cross sectional study

Xiao Di Qin, Zhengmin Qian, Michael G. Vaughn, Edwin Trevathan, Brett Emo, Gunther Paul, Wan Hui Ren, Yuan Tao Hao, Guang Hui Dong

Graduate School of Social Welfare

Research output: Contribution to journal › Article › peer-review

56 Citations (Scopus)

Abstract

Background: Little information exists regarding the interaction effects of obesity with long-term air pollution exposure on cardiovascular diseases (CVDs) and stroke in areas of high pollution. The aim of the present study is to examine whether obesity modifies CVD-related associations among people living in an industrial province of northeast China. Methods: We studied 24,845 Chinese adults, aged 18 to 74years old, from three Northeastern Chinese cities in 2009 utilizing a cross-sectional study design. Body weight and height were measured by trained observers. Overweight and obesity were defined as a body mass index (BMI) between 25-29.9 and ≥30kg/m², respectively. Prevalence rate and related risk factors of cardiovascular and cerebrovascular diseases were investigated by a questionnaire. Three-year (2006-2008) average concentrations of particulate matter (PM₁₀), sulfur dioxide (SO₂), nitrogen dioxides (NO₂), and ozone (O₃) were measured by fixed monitoring stations. All the participants lived within 1km of air monitoring sites. Two-level logistic regression (personal level and district-specific pollutant level) was used to examine these effects, controlling for covariates. Results: We observed significant interactions between exposure and obesity on CVDs and stroke. The associations between annual pollutant concentrations and CVDs and stroke were strongest in obese subjects (OR 1.15-1.47 for stroke, 1.33-1.59 for CVDs), less strong in overweight subjects (OR 1.22-1.35 for stroke, 1.07-1.13 for CVDs), and weakest in normal weight subjects (OR ranged from 0.98-1.01 for stroke, 0.93-1.15 for CVDs). When stratified by gender, these interactions were significant only in women. Conclusions: Study findings indicate that being overweight and obese may enhance the effects of air pollution on the prevalence of CVDs and stroke in Northeastern metropolitan China. Further studies will be needed to investigate the temporality of BMI relative to exposure and onset of disease.

Original language	English
Pages (from-to)	243-248
Number of pages	6
Journal	Science of the Total Environment
Volume	529
DOIs	https://doi.org/10.1016/j.scitotenv.2015.05.041
Publication status	Published - 2015 Oct 1

Bibliographical note

Funding Information:
We are grateful to all participants in the Seven Northeastern Cities for making them available to the study. We would also like to thank the anonymous reviewers for their very helpful comments. This work was supported by the China Environmental Protection Foundation ( CEPF2008-123-1-5 ), and the Guangdong Province Natural Science Foundation ( 1431520600005 ).

Publisher Copyright:
© 2015 Elsevier B.V.

All Science Journal Classification (ASJC) codes

Environmental Engineering
Environmental Chemistry
Waste Management and Disposal
Pollution

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.scitotenv.2015.05.041

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Qin, X. D., Qian, Z., Vaughn, M. G., Trevathan, E., Emo, B., Paul, G., Ren, W. H., Hao, Y. T., & Dong, G. H. (2015). Gender-specific differences of interaction between obesity and air pollution on stroke and cardiovascular diseases in Chinese adults from a high pollution range area: A large population based cross sectional study. Science of the Total Environment, 529, 243-248. https://doi.org/10.1016/j.scitotenv.2015.05.041

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title = "Gender-specific differences of interaction between obesity and air pollution on stroke and cardiovascular diseases in Chinese adults from a high pollution range area: A large population based cross sectional study",

abstract = "Background: Little information exists regarding the interaction effects of obesity with long-term air pollution exposure on cardiovascular diseases (CVDs) and stroke in areas of high pollution. The aim of the present study is to examine whether obesity modifies CVD-related associations among people living in an industrial province of northeast China. Methods: We studied 24,845 Chinese adults, aged 18 to 74years old, from three Northeastern Chinese cities in 2009 utilizing a cross-sectional study design. Body weight and height were measured by trained observers. Overweight and obesity were defined as a body mass index (BMI) between 25-29.9 and ≥30kg/m2, respectively. Prevalence rate and related risk factors of cardiovascular and cerebrovascular diseases were investigated by a questionnaire. Three-year (2006-2008) average concentrations of particulate matter (PM10), sulfur dioxide (SO2), nitrogen dioxides (NO2), and ozone (O3) were measured by fixed monitoring stations. All the participants lived within 1km of air monitoring sites. Two-level logistic regression (personal level and district-specific pollutant level) was used to examine these effects, controlling for covariates. Results: We observed significant interactions between exposure and obesity on CVDs and stroke. The associations between annual pollutant concentrations and CVDs and stroke were strongest in obese subjects (OR 1.15-1.47 for stroke, 1.33-1.59 for CVDs), less strong in overweight subjects (OR 1.22-1.35 for stroke, 1.07-1.13 for CVDs), and weakest in normal weight subjects (OR ranged from 0.98-1.01 for stroke, 0.93-1.15 for CVDs). When stratified by gender, these interactions were significant only in women. Conclusions: Study findings indicate that being overweight and obese may enhance the effects of air pollution on the prevalence of CVDs and stroke in Northeastern metropolitan China. Further studies will be needed to investigate the temporality of BMI relative to exposure and onset of disease.",

author = "Qin, {Xiao Di} and Zhengmin Qian and Vaughn, {Michael G.} and Edwin Trevathan and Brett Emo and Gunther Paul and Ren, {Wan Hui} and Hao, {Yuan Tao} and Dong, {Guang Hui}",

note = "Funding Information: We are grateful to all participants in the Seven Northeastern Cities for making them available to the study. We would also like to thank the anonymous reviewers for their very helpful comments. This work was supported by the China Environmental Protection Foundation ( CEPF2008-123-1-5 ), and the Guangdong Province Natural Science Foundation ( 1431520600005 ). Publisher Copyright: {\textcopyright} 2015 Elsevier B.V.",

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doi = "10.1016/j.scitotenv.2015.05.041",

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Qin, XD, Qian, Z, Vaughn, MG, Trevathan, E, Emo, B, Paul, G, Ren, WH, Hao, YT & Dong, GH 2015, 'Gender-specific differences of interaction between obesity and air pollution on stroke and cardiovascular diseases in Chinese adults from a high pollution range area: A large population based cross sectional study', Science of the Total Environment, vol. 529, pp. 243-248. https://doi.org/10.1016/j.scitotenv.2015.05.041

Gender-specific differences of interaction between obesity and air pollution on stroke and cardiovascular diseases in Chinese adults from a high pollution range area: A large population based cross sectional study. / Qin, Xiao Di; Qian, Zhengmin; Vaughn, Michael G. et al.
In: Science of the Total Environment, Vol. 529, 01.10.2015, p. 243-248.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Gender-specific differences of interaction between obesity and air pollution on stroke and cardiovascular diseases in Chinese adults from a high pollution range area

T2 - A large population based cross sectional study

AU - Qin, Xiao Di

AU - Qian, Zhengmin

AU - Vaughn, Michael G.

AU - Trevathan, Edwin

AU - Emo, Brett

AU - Paul, Gunther

AU - Ren, Wan Hui

AU - Hao, Yuan Tao

AU - Dong, Guang Hui

N1 - Funding Information: We are grateful to all participants in the Seven Northeastern Cities for making them available to the study. We would also like to thank the anonymous reviewers for their very helpful comments. This work was supported by the China Environmental Protection Foundation ( CEPF2008-123-1-5 ), and the Guangdong Province Natural Science Foundation ( 1431520600005 ). Publisher Copyright: © 2015 Elsevier B.V.

PY - 2015/10/1

Y1 - 2015/10/1

N2 - Background: Little information exists regarding the interaction effects of obesity with long-term air pollution exposure on cardiovascular diseases (CVDs) and stroke in areas of high pollution. The aim of the present study is to examine whether obesity modifies CVD-related associations among people living in an industrial province of northeast China. Methods: We studied 24,845 Chinese adults, aged 18 to 74years old, from three Northeastern Chinese cities in 2009 utilizing a cross-sectional study design. Body weight and height were measured by trained observers. Overweight and obesity were defined as a body mass index (BMI) between 25-29.9 and ≥30kg/m2, respectively. Prevalence rate and related risk factors of cardiovascular and cerebrovascular diseases were investigated by a questionnaire. Three-year (2006-2008) average concentrations of particulate matter (PM10), sulfur dioxide (SO2), nitrogen dioxides (NO2), and ozone (O3) were measured by fixed monitoring stations. All the participants lived within 1km of air monitoring sites. Two-level logistic regression (personal level and district-specific pollutant level) was used to examine these effects, controlling for covariates. Results: We observed significant interactions between exposure and obesity on CVDs and stroke. The associations between annual pollutant concentrations and CVDs and stroke were strongest in obese subjects (OR 1.15-1.47 for stroke, 1.33-1.59 for CVDs), less strong in overweight subjects (OR 1.22-1.35 for stroke, 1.07-1.13 for CVDs), and weakest in normal weight subjects (OR ranged from 0.98-1.01 for stroke, 0.93-1.15 for CVDs). When stratified by gender, these interactions were significant only in women. Conclusions: Study findings indicate that being overweight and obese may enhance the effects of air pollution on the prevalence of CVDs and stroke in Northeastern metropolitan China. Further studies will be needed to investigate the temporality of BMI relative to exposure and onset of disease.

AB - Background: Little information exists regarding the interaction effects of obesity with long-term air pollution exposure on cardiovascular diseases (CVDs) and stroke in areas of high pollution. The aim of the present study is to examine whether obesity modifies CVD-related associations among people living in an industrial province of northeast China. Methods: We studied 24,845 Chinese adults, aged 18 to 74years old, from three Northeastern Chinese cities in 2009 utilizing a cross-sectional study design. Body weight and height were measured by trained observers. Overweight and obesity were defined as a body mass index (BMI) between 25-29.9 and ≥30kg/m2, respectively. Prevalence rate and related risk factors of cardiovascular and cerebrovascular diseases were investigated by a questionnaire. Three-year (2006-2008) average concentrations of particulate matter (PM10), sulfur dioxide (SO2), nitrogen dioxides (NO2), and ozone (O3) were measured by fixed monitoring stations. All the participants lived within 1km of air monitoring sites. Two-level logistic regression (personal level and district-specific pollutant level) was used to examine these effects, controlling for covariates. Results: We observed significant interactions between exposure and obesity on CVDs and stroke. The associations between annual pollutant concentrations and CVDs and stroke were strongest in obese subjects (OR 1.15-1.47 for stroke, 1.33-1.59 for CVDs), less strong in overweight subjects (OR 1.22-1.35 for stroke, 1.07-1.13 for CVDs), and weakest in normal weight subjects (OR ranged from 0.98-1.01 for stroke, 0.93-1.15 for CVDs). When stratified by gender, these interactions were significant only in women. Conclusions: Study findings indicate that being overweight and obese may enhance the effects of air pollution on the prevalence of CVDs and stroke in Northeastern metropolitan China. Further studies will be needed to investigate the temporality of BMI relative to exposure and onset of disease.

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Qin XD, Qian Z, Vaughn MG, Trevathan E, Emo B, Paul G et al. Gender-specific differences of interaction between obesity and air pollution on stroke and cardiovascular diseases in Chinese adults from a high pollution range area: A large population based cross sectional study. Science of the Total Environment. 2015 Oct 1;529:243-248. doi: 10.1016/j.scitotenv.2015.05.041

Gender-specific differences of interaction between obesity and air pollution on stroke and cardiovascular diseases in Chinese adults from a high pollution range area: A large population based cross sectional study

Abstract

Bibliographical note

All Science Journal Classification (ASJC) codes

UN SDGs

Access to Document

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