Abstract
Spatiotemporal focussing has enabled widefield, axially confined multiphoton excitation. Its main advantage of an improved performance through scattering media, useful for deep imaging and optogenetics, however, has largely been evaluated empirically because of a lack of a suitable computational model. To overcome this we have developed a full-wave simulation describing two-photon microscopy image formation through scattering media with spatiotemporal focussing. This model provides full freedom to vary imaging parameters and observe quantities not generally accessible in experiment. We use this model to reveal new insights into the properties of spatiotemporal focussing in the presence of scattering media.
| Original language | English |
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| Title of host publication | 2022 IEEE Photonics Conference, IPC 2022 - Proceedings |
| Publisher | Institute of Electrical and Electronics Engineers Inc. |
| ISBN (Electronic) | 9781665434874 |
| DOIs | |
| Publication status | Published - 2022 |
| Event | 2022 IEEE Photonics Conference, IPC 2022 - Vancouver, Canada Duration: 2022 Nov 13 → 2022 Nov 17 |
Publication series
| Name | 2022 IEEE Photonics Conference, IPC 2022 - Proceedings |
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Conference
| Conference | 2022 IEEE Photonics Conference, IPC 2022 |
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| Country/Territory | Canada |
| City | Vancouver |
| Period | 22/11/13 → 22/11/17 |
Bibliographical note
Publisher Copyright:© 2022 The Author(s)
All Science Journal Classification (ASJC) codes
- Control and Optimization
- Instrumentation
- Atomic and Molecular Physics, and Optics
- Artificial Intelligence
- Computer Networks and Communications
- Electrical and Electronic Engineering
- Global and Planetary Change
- Management, Monitoring, Policy and Law