Fluorescent glycan derivatives: Their use for natural glycan microarrays

Sungjin Park; Jung Won Sung; Injae Shin

doi:10.1021/cb9002078

Fluorescent glycan derivatives: Their use for natural glycan microarrays

Sungjin Park, Jung Won Sung, Injae Shin

Department of Chemistry

Research output: Contribution to journal › Short survey › peer-review

16 Citations (Scopus)

Abstract

Glycan microarrays have become powerful tools in the investigation of biological systems because they enable fast, quantitative, and simultaneous analysis of glycan - protein interactions with small quantities of samples. One hurdle in the construction of glycan microarrays is to obtain a diverse set of glycans for immobilization on surfaces. An article in this issue of ACS Chemical Biology describes the microscale preparation of fluorescently labeled reactive glycans in a cyclic form of the reducing sugar, from natural sources, that can be utilized directly to create natural glycan microarrays for use in functional glycomics.

Original language	English
Pages (from-to)	699-701
Number of pages	3
Journal	ACS Chemical Biology
Volume	4
Issue number	9
DOIs	https://doi.org/10.1021/cb9002078
Publication status	Published - 2009 Sept 18

All Science Journal Classification (ASJC) codes

Biochemistry
Molecular Medicine

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10.1021/cb9002078

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AU - Shin, Injae

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AB - Glycan microarrays have become powerful tools in the investigation of biological systems because they enable fast, quantitative, and simultaneous analysis of glycan - protein interactions with small quantities of samples. One hurdle in the construction of glycan microarrays is to obtain a diverse set of glycans for immobilization on surfaces. An article in this issue of ACS Chemical Biology describes the microscale preparation of fluorescently labeled reactive glycans in a cyclic form of the reducing sugar, from natural sources, that can be utilized directly to create natural glycan microarrays for use in functional glycomics.

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Fluorescent glycan derivatives: Their use for natural glycan microarrays

Abstract

All Science Journal Classification (ASJC) codes

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