Abstract
We have analyzed the effectiveness of field-matter integral overlap between target index distribution and local near-fields to assess detection sensitivity of surface plasmon resonance (SPR) biosensors. The correlation of the overlap with sensitivity was clear. An overlap integral defined with lateral electric field intensity produced the highest correlation due to tangential continuity across a boundary. Among the three detection scenarios considered, the correlation for localized SPR sensing was slightly lower than that of thin film-based detection and improved with an increased fill factor in the structure. The results will be useful to maximize the optical signature created by target interactions and to produce highest sensitivity of SPR detection to variations when target or field distribution is not uniform.
| Original language | English |
|---|---|
| Pages (from-to) | 1367-1376 |
| Number of pages | 10 |
| Journal | Journal of the Optical Society of America A: Optics and Image Science, and Vision |
| Volume | 29 |
| Issue number | 7 |
| DOIs | |
| Publication status | Published - 2012 Jul 1 |
All Science Journal Classification (ASJC) codes
- Electronic, Optical and Magnetic Materials
- Atomic and Molecular Physics, and Optics
- Computer Vision and Pattern Recognition