TY - JOUR
T1 - Factors Determining Early Left Atrial Reverse Remodeling After Mitral Valve Surgery
AU - Cho, Deok Kyu
AU - Ha, Jong Won
AU - Chang, Byung Chul
AU - Lee, Se Hwa
AU - Yoon, Se Jung
AU - Shim, Chi Young
AU - Cho, Jung Rae
AU - Kim, Jung Sun
AU - Choi, Eui Young
AU - Rim, Se Joong
AU - Chung, Namsik
PY - 2008/2/1
Y1 - 2008/2/1
N2 - This study aimed to investigate the factors determining early left atrial (LA) reverse remodeling after mitral valve (MV) surgery. The left atrium is frequently dilated in patients with mitral stenosis (MS) or mitral regurgitation (MR). MV surgery usually results in LA volume reduction. However, the factors associated with LA reverse remodeling after MV surgery are not clearly defined. One hundred thirty-eight patients (51 men, 87 women; mean age, 53 years) underwent transthoracic echocardiography before and after MV surgery. Maximal LA volume was measured using the prolate ellipsoid model. The percentage of LA volume change was calculated. The patients were grouped according to age (<50 vs ≥50 years), predominant lesion (pure MR vs some degree of MS), type of surgery (MV repair vs MV replacement), and preoperative rhythm (sinus rhythm vs atrial fibrillation). LA volume decreased from 147 ± 93 to 103 ± 43 ml (p <0.001) after surgery. LA reverse remodeling was more prominent in patients who were <50 years old (percentage of LA volume change -31.2 ± 17.4 vs -18.4 ± 19.2, p <0.001), had pure MR (percentage of LA volume change -30.4 ± 18.6 vs -17.3 ± 18.2, p <0.001), and had a preoperative sinus rhythm (percentage of LA volume change -28.5 ± 17.7 vs -20.5 ± 20.0, p = 0.019). In conclusion, on stepwise multiple regression analysis, preoperative LA volume, predominant lesion, age, and cardiac rhythm were significant predictors of LA reverse remodeling. A larger preoperative LA volume, MR rather than MS, younger age at the time of surgery, and sinus rhythm were important predictors of LA reverse remodeling after MV surgery.
AB - This study aimed to investigate the factors determining early left atrial (LA) reverse remodeling after mitral valve (MV) surgery. The left atrium is frequently dilated in patients with mitral stenosis (MS) or mitral regurgitation (MR). MV surgery usually results in LA volume reduction. However, the factors associated with LA reverse remodeling after MV surgery are not clearly defined. One hundred thirty-eight patients (51 men, 87 women; mean age, 53 years) underwent transthoracic echocardiography before and after MV surgery. Maximal LA volume was measured using the prolate ellipsoid model. The percentage of LA volume change was calculated. The patients were grouped according to age (<50 vs ≥50 years), predominant lesion (pure MR vs some degree of MS), type of surgery (MV repair vs MV replacement), and preoperative rhythm (sinus rhythm vs atrial fibrillation). LA volume decreased from 147 ± 93 to 103 ± 43 ml (p <0.001) after surgery. LA reverse remodeling was more prominent in patients who were <50 years old (percentage of LA volume change -31.2 ± 17.4 vs -18.4 ± 19.2, p <0.001), had pure MR (percentage of LA volume change -30.4 ± 18.6 vs -17.3 ± 18.2, p <0.001), and had a preoperative sinus rhythm (percentage of LA volume change -28.5 ± 17.7 vs -20.5 ± 20.0, p = 0.019). In conclusion, on stepwise multiple regression analysis, preoperative LA volume, predominant lesion, age, and cardiac rhythm were significant predictors of LA reverse remodeling. A larger preoperative LA volume, MR rather than MS, younger age at the time of surgery, and sinus rhythm were important predictors of LA reverse remodeling after MV surgery.
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U2 - 10.1016/j.amjcard.2007.09.076
DO - 10.1016/j.amjcard.2007.09.076
M3 - Article
C2 - 18237603
AN - SCOPUS:38549089068
SN - 0002-9149
VL - 101
SP - 374
EP - 377
JO - American Journal of Cardiology
JF - American Journal of Cardiology
IS - 3
ER -